meiosis and variation Flashcards
Meiosis
cell division that reduces the chromosome number by half, producing genetically different cells
homologous chromosomes
pair of chromosomes, one from each parent, with genes for the same traits
bivalents
paired homologous chromosomes during prophase 1
chiasmata
points where crossing over occurs
haploid
- n
- single set of chromosomes
diploid
2n
two sets of chromosomes
what is the function of meiosis
produce gametes
two rounds of division in meiosis
meiosis I
meiosis II
purpose of meiosis 1
separate the homologous chromosomes, reducing the chromosome number by half
what happens before meiosis 1
the 2 sets of chromosomes in the nucleus replicate during interphase
prophase 1
- chromosomes condense as bivalents
- crossing over occurs at the chiasmata
- spindle fibres form, and nuclear membrane disintegrates
metaphase 1
- homologous pairs align along the equator of the cell
- random orientation of homologous pairs introduces an independent assortment
anaphase 1
- homologous chromosomes are pulled to opposite poles by spindle fibres
- sister chromatids remain attached at the centromeres
telophase 1 and cytokinesis
- nuclear membranes reform around two haploid sets
- cell divides into 2 haploid cells
meiosis II purpose
separates sister chromatids to produce four haploid cells
prophase II
- chromosomes condense again
- spindle fibres form in each haploid cell
metaphase II
- chromosomes align at the equator
- sister chromatids are oriented towards opposite poles
anaphase II
sister chromatids are separated and pulled to opposite poles
telophase II and cytokinesis
- nuclear membrane reforms around the chromosomes in each four cells
- cytoplasm divides
- produces 4 genetically unique haploid cells
how can variation happen in meiosis
- crossing over in prophase I
- independent assortment in metaphase 1
- mutation
cetromere
site of attachment of spindle fibers
Explain how meiosis can lead to variation (5marks)
- During prophase 1 of meiosis, homolohous chromosomes pair up and exchange genetic material at points called chiasmata. This is known as crossing over, resulting in new combination of alleles on the chromatids, increasing variation among offspring.
2.
In metaphase I, homologous chromosomes line up randomly along the equator of the cell. This random allignement means that different combinations of maternal and paternal chromosomes can be inherited, leading to g enetic variation in the gametes.
what is the significance of meiosis
- offers a mechanism for some genetic stability.
- meiosis leads to genetic variation.
meiosis vs. mitosis: similarities
- replication of the DNA in interphase
- replication of cell organelles
- similar stages of PMAT
- formation of a spindle
differences of mitosis and meiosis
- mitosis consists of one division, and meiosis has 2
- mitosis involves the separation of sister chromatids, meiosis is the separation of homologous chromosomes+ separation of chromatids
- no crossing over occurs in mitosis
- no chiasmata is formed in mitosis
- daughter nuclei have same number of chromosomes as parent nucleus in mitosis, meiosis is half
- no genetic variation in daughter nuclei in mitosis