Mehl. HTN Flashcards

1
Q

chronic HTN. definition?

A

“Chronic hypertension” = HTN prior to the pregnancy or diagnosed before 20 weeks’ gestation;

usually persists postpartum since BP present in early pregnancy, or prior to
it, often reflects underlying issue unrelated to the pregnancy.

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2
Q

chronic HTN. Can pre-exist or persist beyond pregnancy, while gestational hypertension is specific to the pregnancy period. Both conditions require close monitoring due to potential risks to the mother and fetus.

A

.

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3
Q

Gestational HTN. definition?

A

new-onset HTN that develops after 20 weeks’ gestation;
typically resolves postpartum.

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4
Q

What drugs can be used to for chronic and gestational HTN.? 4

A

Both chronic and gestational HTN can be managed with methyldopa (a2
agonist), labetalol, or nifedipine.
Hydralazine can be used in acute settings.

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5
Q

Preeclampsia. True Obgyn definition is more expansive to incorporate signs of damage to other
organs, but for USMLE, 4/5 Qs will just be HTN + proteinuria.

A

.

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6
Q

In Qs that don’t give you the strict HTN >20 weeks’ gestation + proteinuria combo,
they will usually just give straight-up HELLP syndrome (discussed below), which is considered to be a severe form of preeclampsia involving damage to the liver.

A

.

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7
Q

Eclampsia definition?

A

preeclampsia + seizures.

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8
Q

Mechanism for preeclampsia/eclampsia?

A

uteroplacental insufficiency, where
inadequate perfusion to the placenta causes a compensatory attempt by the
cardiovascular system to increase/force perfusion, thereby resulting in systemic HTN.

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9
Q

The uteroplacental insufficiency can be?

A

idiopathic or due to secondary factors such as smoking and SLE.

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10
Q

“Severe preeclampsia”?

A

BP > 160/110 (either number), proteinuria 3+ on dipstick, or
any evidence of multi-organ system involvement (i.e., liver, CNS, lungs). L

iver damage
can be overt HELLP syndrome or just any elevation in hepatic enzymes.

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11
Q

CNS involvement can refer to visual disturbance or headache. Pulmonary involvement refers to pulmonary edema or cyanosis.

A

.

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12
Q

When is given Mg?

A

Magnesium is only given prophylactically to prevent eclampsia (seizures) if patient
has severe preeclampsia.

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13
Q

If patient already has overt eclampsia with seizures, first Tx is magnesium.

nu cia taip buvo parasyta, bet pries tai buvo mineta kad mg tik profilaktikai kai preeclampsia

A

.

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14
Q

Definitive management for both preeclampsia and eclampsia?

A

delivery of the fetus.

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15
Q

HELLP abreviation?

A

Hemolysis, Elevated Liver enzymes, Low Platelet count.

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16
Q

HELLP. As mentioned above, a severe variant of preeclampsia.

A

Q might not even mention proteinuria. Doesn’t matter.

17
Q

HELLP. HY?

A

Highest yield point for USMLE is that we see schistocytes on a blood smear. This is
due to RBC shearing that occurs within hepatic damaged microvasculature.

18
Q

HELLP. why decr. PLT?

A

Platelets fall as a result of microvascular endothelial cell dysfunction/damage, where microthrombi form in an attempt to mitigate damage.

19
Q

HELLP. what anemia?

A

The combination of schistocytosis and thrombocytopenia is called microangiopathic
hemolytic anemia (MAHA).