MEH practice Flashcards
A women is suffering from heavy menstrual bleeding, feeling tied, weak and short of breath.
Her Hb count and RBC count is low, which further abnormality would you expect
low iron
mutation of the gene coding …… , can cause hereditary spherocytosis
ankryin
which abnormality in which white blood cells occurs after an asthma attach
eosinophilia
what can precipitate Haemolysis in a patient with glucose-6- phosphate dehydrogenase deficiency?
anti-malarials
why can anti-malarial precipitate Haemolysis in a patient with glucose-6- phosphate dehydrogenase deficienc
antimalarials such as primaquine oxidase glutathione further depletes the levels of reduced GSH leaving cells very susceptible to oxidative damage
what is the primary abnormality in patients presenting with DKA (diabetic ketoacidosis)
absolute insulin deficiency leading to ketone production
which enzyme is most likely to be deficiency in classical (type 1) galactosaemia where both galactose and galactose 1-phosphate accumulate in tissues
galactose 1-phosphate dehydrogenase
which enzyme is most likely to be deficient in the form of galactosaemia in which the symptoms are less severe and in which only galactose accumulates in the blood tissue
galactokinase
what does high alkaline phosphatase suggest
increased bone turnover
normal range in fasting blood glucose
3.3-6.0 mmol/l
tests reveal an abnormally high conc of creatinine in his blood but a lower normal level of creatinine in his urine. Which condition is best indicated?
decreased kidney function
what do these symptoms suggest: weight losss, intermittent severe abdominal pain radiation down the back. Uralysis shows glucose ++
chronic pancreatitis
sequence of lipoproteins in order or most to least dense
HDL –> LDL–> VLDL –> chylomicrons
which enzyme plays an important role int he bodies immune response to infection
NADPH oxidase (neutrophils and monocytes) - resp burst
Glutathione requires which trace element to function
selenium
mechanism of disulfirum
inhibition of aldehyde dehydrogenase
hormone responsible for short-term regulation of serum calcium
parathyroid hormone
calcitriole (active form of vitamin D)
responsible for longer term regulation (increase_
BMI of 26
overweight
BMI of 30
obese
side effect of addisons
hyperpigmentation
ACTH mediated melanocyte stimulation
