Medocs Flashcards

1
Q

EI fluoroquinolones

A
Phototoxicité
Tendinopathies 
Neuropsychiques 
Hépatites 
Allongement QT
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2
Q

Atb à bonne pénétration osseuse

A
  • rifampicine
  • FQ
  • acide fusidique
  • clindamycine
  • cyclines
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3
Q

Atb ci femme enceinte

A
  • cyclines
  • quinolone
  • aminosides
    Ci T1: rifampicine/ cotrimoxazole (bactrim)
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4
Q

Listeria et entérocoque sont résistants à quel type atb ?

A

C3G

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5
Q

Mécanisme de résistance aux atb?

A
  • mutations
  • inactivation enzymatique
  • modif cible
  • dim perméabilité membranaire
  • augmentation meca d’efflux
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6
Q

Atb bactéricides temps dépendant et concentration dependante

A
  • Tps dépendant : beta lactamines ( pénicilline + cephalosporines) et glycopeptide ( vancomycine )
  • concentration dépendante : aminosides, rifampicine, fluoroquinolones
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7
Q

Atb augmentant le QT

A
  • fluoroquinolones

- macrolides

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8
Q

Principale toxicité ganciclovir

A

Myelotoxicité

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9
Q

Antibio ayant activité anti toxinique

A
  • clindamycine
  • rifampicine
  • linezolide
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