Medications Test 3

Question 1

2nd Generation Sulfonylureas

-Examples

Answer 1

1. Glipizide (Glucotrol)
2. Glyburide (Glynase)
3. Glimepriride (Amaryl

Question 2

2nd Generation Sulfonylureas

-Action

Answer 2

1. Works to increase output of insulin by beta cells in pancreas

Question 3

2nd Generation Sulfonylureas

-Side Effects

Answer 3

1. Hypoglycemia w/ delayed or skipped meals or alcohol

Question 4

2nd Generation Sulfonylureas

-Implications

Answer 4

1. Use cautiously in elderly

2. Best taken 30 Min prior to meal

Question 5

Biguanide

-Examples

Answer 5

1. Metformin (Glucophage)

Question 6

Biguanide (Metformin)

-Action

Answer 6

1. Decrease liver output of sugar

2. Increase peripheral insulin sensitivity

Question 7

Biguanide (Metformin)

-Side Effects

Answer 7

1. GI distress
2. DIarrhea
3. Lactic acidosis

Question 8

Biguanide (Metformin)

-Contraindications

Answer 8

1. CHF
2. Alcohol abuse
3. Metabolic acidosis
4. Liver or kidney disease
5. Pt is >80 yrs old

Question 9

Biguanide (Metformin)

-Implications

Answer 9

1. Kidney surveillance testing required
   - Monitor serum creatinine
2. Take w/ food
3. Discontinue after OR, dye (contrast) studies for 48 hrs or until kidney function normal

Question 10

Insulin (Very Rapid Acting)

-Examples

Answer 10

1. Lispro (Humalog)

2. Aspart (Novalog)

Question 11

Insulin (Very Rapid Acting)

-Action

Answer 11

1. Onset: 10 minutes
2. Peak: 1 hr
3. Lasts: 3-4 hrs

Question 12

Insulin (Very Rapid Acting)

-Implications

Answer 12

1. Clear solution

2. Give 15 min prior to meal

Question 13

Insulin (Short (Rapid) Acting)

-Example

Answer 13

Regular (R)

Question 14

Insulin (Short (Rapid) Acting)

-Action

Answer 14

1. Onset: 30 min
2. Peaks: 3-5 hrs
3. Lasts: 6-10 hrs

Question 15

Insulin (Short (Rapid) Acting)

-Implications

Answer 15

1. Clear Solution

2. Give 30 minutes prior to meal

Question 16

Insulin (Intermediate Acting)

-Examples

Answer 16

1. NPH

2. Lente

Question 17

Insulin (Intermediate Acting)

-Action

Answer 17

1. Onset: 1 hr
2. Peaks: 6-12 hrs
3. Lasts: 20-24 hrs

Question 18

Insulin (Intermediate Acting)

-Implications

Answer 18

1. Cloudy Solution

2. Rotate prior to use

Question 19

Long Acting Insulin

(Glargine (Lantus) - Action

Answer 19

1. Onset: 1 hr
2. No peak
3. Lasts: 24 hrs

Question 20

Long Acting Insulin

(Glargine (Lantus) -Implications

Answer 20

1. Clear solution

2. Do not mix with others

Question 21

Long Acting Insulin

(Detemir (Levemir) - Action

Answer 21

1. Onset: 3-4 hrs
2. No peak
3. Lasts: 24 hrs

Question 22

Long Acting Insulin

(Detemir (Levemir) - Implications

Answer 22

1. Clear solution

2. Do not mix w/ others

Question 23

Antithyroid Agent

- Example

Answer 23

1. Methimazol ( Tapazole)

Question 24

Antithyroid Agent

-Action

Answer 24

1. Inhibits synthesis of thyroid hormones

Question 25

Antithyroid Agent

-Implications

Answer 25

1. Monitor thyroid function and hepatic function

Question 26

Thyroid Supplement

-Example

Answer 26

1. Levothyroxine (Synthroid)

Question 27

Thyroid Supplement

-Action

Answer 27

1. Synthetic thyroid hormone

Question 28

Thyroid Supplement

-Implication

Answer 28

1. Give on empty stomach, 1/2 hr prior to breakfast

2. Monitor thyroid function