Medications: Endocrine Flashcards
What is the trade name for Levothyroxine?
Synthroid
What is the generic name for Synthroid?
Levothyroxine
How does Levothyroxine (Synthroid) work in the body?
Levothyroxine (Synthroid) is an exogenous hormone
Levothyroxine (Synthroid) is a synthetic preparation of thyroxine (T4)
When in the body, it converts into T3
What time of the day is Levothyroxine (Synthroid) administered? Why is it administered at this time?
Given early in the morning on an empty stomach
Must be given 30-60 minutes before food ingested so it is absorbed fully
What route is Levothyroxine (Synthroid) given?
Administered via PO route
Why is Levothyroxine (Synthroid) given?
To treat hypothyriodism
It is the drug of choice for thyroid hormone replacement
What kind of dose of Levothyroxine (Synthroid) is the patient started on initially (low dose or high dose)? Why?
Started on a low dose
Gradually increased
This is done to prevent hyperthyroidism from occurring
What education regarding signs ang symptoms does the nurse need to provide when a patient begins Levothyroxine (Synthroid)?
Watch out for s/s of hyperthyroidism
S/S include: tachycardia, angina (chest pain), palpitations, tremors, nervousness, hyperthermia, heat intolerance, sweating
Notify provider ASAP if these s/s occur
If a patient experiences hyperthyroidism s/s when taking Levothyroxine (Synthroid), what needs to occur?
Patient must notify provider
Provider will decrease the dose
What is the drug class of Levothyroxine (Synthroid)?
Thyroid Hormone Replacement
What is the drug class for Metformin (Glucophage, Fortamet)?
Biguanide
Name a medication that falls under the drug class Biguanide.
Metformin (Glucophage, Fortamet)
What are trade names for Metformin?
Glucophage
Fortamet
What is the generic name for Glucophage or Fortamet?
Metformin
How does Metformin (Glucophage, Fortamet) work?
It decreases the glucose produced by the liver
It increases the amount of glucose uptake by the muscles
Does Metformin (Glucophage, Fortamet) directly decrease blood sugar? Is there a direct risk for hypoglycemia?
No it does not. It does not increase insulin production or release.
No direct risk for hypoglycemia
How is Metformin (Glucophage, Fortamet) administered? When is it given?
PO
Daily or multiple times a day
What is one reason Metformin (Glucophage, Fortamet) is given?
To help control blood sugar and Hgb A1C levels in the patient with Diabetes Mellitus Type Two
Can a patient with Diabetes Mellitus Type One take Metformin (Glucophage, Fortamet) for blood sugar control? Why or why not?
No.
The patient with Diabetes Mellitus Type One must take exogenous insulin to survive.
What organ can Metformin (Glucophage, Fortamet) damage? What labs need to be monitored?
It can damage the kidneys
Monitor BUN, Crt, eGFR
Must assess these labs prior to starting the medication and while taking it.
If the patient has a diagnostic imaging test with IV contrast scheduled, what must the nurse do regarding scheduled Metformin (Glucophage, Fortamet) to be given?
Contact physician. Do not give Metformin (Glucophage, Fortamet). It will damage the kidneys.
Name medications that fall under the drug class Sulfonylureas
Glipizide (Glucotrol)
Glimeperide (Amaryl)
Glyburide (Micronase)
The medications Glipizide (Glucotrol), Glimeperide (Amaryl), Glyburide (Micronase) fall under what drug class?
Sulfonylurea