Medical / Surgical Management of Pulmonary Dysfunction Flashcards
Smoking cessation medications:
- Nicotine Replacement Therapy: patch, gum, tablets, inhalers.
- Bupropion (Zyban): antipressant: helps reduce cravings & withdraw effects.
- Varenincline: nicotine receptor agonist
Codeine, hydrocodone
- Opioids
- Antitussives
- Cough medication
- Supress cough reflex
Antihistamines:
- block histamine receptor
- decrease nasal congestion, sinusitis & allergies
- benadryl, claritin
Antitussives:
- Cough medication
- Opioids
- codeine, hydrocodone
decrease nasal congestion, sinusitis & allergies
Antihistamines
benadryl, claritin
Mucolytics and Expectorants:
- Mucolytics break up mucus in the airways.
- Expectorants: facilitate mucus secretion and clearance.
- Mucomyst, pulmozyme, guaifenesin (mucinex).
alpha receptor agonist
- Decongestant
- Alpha1 receptors: constrictor, post-sypnaptic, norepinephrine
- Vasoconstriction
- increases BP
Beta2-agonists are a type of ______________. This means that they relax and enlarge (dilate) the airways in the lungs, making breathing easier.
bronchodilator
_____________ cause relaxation of smooth muscle by activating Beta2 receptors and inhibiting respiratory smooth muscle contraction.
Beta2 agonists
Beta2 agonists are selective for
respiratory tissues
Bronchodilators
Theophylline:
- Bronchodilator.
- Relax airway smooth muscle, also has some anti-inflammatory effects.
3 types of bronchodilators:
- Beta2 Agonist (beta-adrenergic agonist): inhibit smooth muscle contraction.
- Theophylline: relax airway smooth muscle, also has some anti-inflammatory effects
- Anticholinergics: inhibit acetylcholine activity.
Anticholinergics:
- Bronchodilator
- Decreased acetylcholine activity at various sites. So inhibition of this facilitates bronchodilation.
- Not specific to pulmonary system.
What type of bronchodilator is specific to the pulmonary system?
Beta2 agonist (beta-adrenergic agonist)
What type of bronchodilator is not specific to the pulmonary system?
Anticholinergics
Decrease acetylcholine activity at various sites of the body, including the lungs. So inhibition of this facilitates bronchodilation.
- Oral prednisone, methylprednisolone.
- Inhaled: triamcinolone, beclomethasone, fluticasone.
are what type of medications?
corticosteroids, glucocorticoids
Anti-inflammatory Medications
best anti-inflammatory medication but worse side effects
corticosteroids - glucocorticoids
side effects of glucocorticoids
- osteoporosis
- steroid myopathy
- HTN, gastric ulcers, exacerbation of DM, steroid induced DM, glaucoma, adrenal gland suppression, skin breakdown.
Leukotriene modifiers
- Impact how leukotrienes work.
- Leukotrienes are inflammatory molecules made by WBC that cause bronchoconstriction and augment inflammatory response.
- Montelukast (singulair)
Prevent inflammation of the airways by inhibiting releasing of inflammatory mediators from cells in respiratory mucosa.
Cromones
Must be taken before exposure to allergen/irritant. Help preventing attacks. Prevent inflammation of the airways by inhibiting releasing of inflammatory mediators from cells in respiratory mucosa.
Cromones
Cromolyn
if pt has exercise induced asthma
bring short acting bronchodilator to PT session
When a pt is taking corticosteroids, the therapist should be aware of
thinning of the skin and weakening of bones
what should a therapist should be aware when a patient is taking theophylline
increase in heart rate, abnormal heart rhythms, and CNS excitation
reduce size by removing %ge of diseased lung tissue (emphysema) → room for lung to expand.
Lung Volume Reduction Surgery
Pneumonectomy:
removal of entire lung.