Exercise Physiology Flashcards
Convective O2 transport
movement of O2 in air or blood
Diffusive O2 transport
passive movement of O2 down concentration gradient across tissue barriers.
- Volume of oxygen delivered to systemic vascular bed per minute.
- The product of cardiac output and arterial oxygen content.
Oxygen Delivery (DO2)
DO2
Oxygen delivery to systemic vascular bed per minute
CO ✖️ arterial oxygen content
VO2
Oxygen Consumption
amount of oxygen a person requires
Amount of oxygen that diffuses from capillaries to mitochondria
Oxygen Consumption VO2
OER
Oxygen extraction ratio (OER):
Tissue oxygenation is adequate when tissues receive sufficient oxygen to meet their metabolic needs.
arterial oxygen x cardiac output =
Oxygen Delivery DO2
(CO = HR x stroke volume)
at rest DO2….
decreases
with activity DO2…
increases
Stroke Volume is affected by:
- Pre-load
- Myocardial distensibility.
- Myocardial contractability.
- Afterload.
Cardiac output =
Stroke volume x HR
Ways to measure VO2:
- Take arterial and venous blood and see the difference.
- Exercise breath test.
VO2 ➗ weight in Kg =
VO2
VO2 =
Volume inspired – volume expired
Rate of metabolism in a completely rested state (morning after waking up)
Basal Metabolic Rate
(resting metabolic rate)
Is there any difference between “Basal Metabolic Rate” and “Resting Metabolic Rate”?
basal = completely doing nothing but breathing
resting = sitting and doing minimal movt
Amount of oxygen consumed while sitting at rest:
Metabolic Equivalent MET
1 MET =
3.5 mL O2/Kg/Min
Energy cost of an activity: MET Level =
VO2 ➗ 3.5
V02 and DO2 at rest
DO2 can be 2-4 times greater than VO2
oxygen delivery is greater than oxigen consumption
DO2 and VO2 during exercise:
- Oxygen consumption increases up to 20-fold
- So the body increases RR and HR
- Blood flow increases
- Blood vessel dilatation increases availability of O2 and extractions from blood
Increase in VO2 and DO2
If DO2 declines, what happens to VO2?
- Regardeless of oxygen delivery, muscle will consume need to consume the same amount.
- Will not affect VO2
After strenuous exercise, there are 4 tasks that need to be completed:
- Replenishment of ATP
- Replenishment of myoglobin with oxygen.
- Replenishment of glycogen.
- Removal of lactic acid.
Functionally, myoglobin is well accepted as an
- O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia.
- High concentrations of myoglobin in muscle cells allow organisms to hold their breath for a longer period of time.
difference between oxygen demand and oxygen consumption
Oxygen debt
true or false: oxygen extraction is enhanced with exercise stress.
true