Diagnostic Testing Flashcards
Cytology:
Analysis of cells: how they form and function.
Laboratory tests:
- Cytology: analysis of cells: how they form and function
- Hematology: complete blood count, WBC, RBC, platelets.
- Coagulation studies: how well id the blood clotting (partial thromboplastin time, prothrombin time)
- Arterial Blood Gas (ABG): alveolar ventilation, oxygenation, acid-base balance, disease progression.
Arterial Blood Gas (ABG) can give information about
- alveolar ventilation
- oxygenation
- acid-base balance
- disease progression
would the venous blood gas lab result be the same as arterial blood gas?
no
PaCO2 > 50 =
respiratory failure
- Failure of pulmonary system to meet metabolic demands of body
- Extent of failure is determined by accompanying change in pH
Acidosis + low HCO3 =
primary
metabolic acidosis
Is the problem uncompensated or compensated/compensating? Look at…
CO2
-
UNCOMPENSATED
- pH is outside the normal range
- PaCO2 is within the normal range
-
PARTIALLY COMPENSATED
- Both pH and PaCO2 are outside the normal range
-
COMPENSATED
- pH is within normal range
- PaCO2 is outside normal range
Chronic respiratory acidosis: kidneys __________ bicarbonate
hold
Corresponding increase/decrease in HCO3- which indicates that the _____________ system is compensation
metabolic
Corresponding increase/decrease in PaCO2 which indicates that the _____________ system is compensation
respiratory
Kidneys can compensate for chronic respiratory disorders by either holding or dumping bicarbonate. Chronic respiratory acidosis: kidneys __________ bicarbonate
hold
In chronic respiratory alkalosis: kidneys will __________ bicarbonate
get rid of
crime = acid police = Bicarbonate (HCO3) criminals = H+
nice
to get rid of the crime, the police hold on to criminals to be excreted by the kidneys
What affects Forced Vital Capacity?
Restrictive diseases
(fibrosis, scoliosis, diaphgram can’t move, obesity, pulmonary edema…)
Forced Expiratory Volume in 1 sec
- Reflects airflow in large (& medium sized) airways
- 75% - 80% of FVC should be exhaled in the first second
- If decreased = obstructive disease
- Large lungs = large FEV1
- Large airway diameter = large FEV1
Measure volume and flow of air during inspiration and exhalation
Pulmonary Function Testing (PFT)
Provides graphic display of inspiratory and expiratory flows and volumes
Flow volume loops
Max amt of gas pt can exhale forcefully & quickly
Forced Vital Capacity (FVC)
FEV1/FVC
- Decreased = obstructive disease
- Near normal or elevated = restrictive disease
Normal Forced Vital Capacity
80%
- Mild: 60-79%
- Moderate: 51-59%
- severely impaired < 50
Normal Forced Expiratory Volume in 1 second:
80%
- Mild: 60-79%
- Moderate 51-49%
- Severe < 40%
Normal FEV1/FVC =
75%
- Mild 60-74%
- Moderate: 41-59%
- Severe: <40%
What causes FVC to decrease?
restriction diseases, whatever restricts air into the lungs:
fibrosis, scoliosis, obesity, diaphragm can’t move.
What causes Forced Expiratory Volume in 1 sec to decrease?
obstructive diseases
- if FEV1 and FEV1/FVC = decreased (less than 75%)
- RV = increased
- TLC = normal or increased
obstruction