Medical Flashcards
Cyanokit medication -
Two vials contains 2.5g of hydroxocobalamin. Adults get both vials
= inhibit the parasympathetic nervous system by BLOCKING the action of acetylcholine. Patient are hyper, tachy, fever. Examples Atropine, Antihistamines, antipsychotics, antispasmodics, cyclic antidepressants, mydriatics. Also plants and mushrooms
Anticholinergic drugs
= STIMULATE the parasympathetic nervous system by activating receptors for acetylcholine.
Symptoms = SLUDGE, salivation, lacrimation, urination, defecation, gastrointestinal distress, and eyes (dilation).
Cholinergic drugs
anticholinergic vs sympathomimetic toxidromes
= Both have fever, tachycardia, hypertension, mydriasis and mental status changes. However, anticholinergic patient has dry, red (flushed) skin, constipation and delirium while the sympathomimetic patient has pale, diaphoretic skin, increased GI motility and is typically agitated.
Opioid vs sedative-hypnotic toxidromes
= Opioid toxidrome has miosis and respiratory depression while the sedative-hypnoitic toxidrome have any size pupils and rarely has respiratory depression.
Opioid drugs receptors
= G-protein coupled receptors (GCPR) that are found exclusively in the central nervous system. Withdrawal treated with long acting opioid agonist such as methadone, buprenorphine, clonidine,
Epinephrine, cocaine, amphetamines, MDMA, and over the counter drugs containing ephedrine. Direct stimulation of the alpha- and beta-adrenergic receptors. Restraining may lead to death. Give benzodiazepines (Diazepam)
Sympathomimetic Toxicity
Beta blocker toxicity
- Beta1-receptor blockade impact heart and BP.
- Beta2-receptor blockade inhibits relaxation of smooth muscle in blood vessels, bronchi, etc.
- Bradycardia, hypotension, arrhythmias, hypothermia, hypoglycemia, and seizures.
- We give Glucagon
Calcium Channel Blocker toxicity =
Hypotension, brady-dysrhythmia, and cardiac arrest, depressed level of consciousness. Give activated charcoal
Organophosphate toxicity
= three broad impact categories: Muscarinic effects, Nicotinic effects, Central nervous system
Neuropsychiatric effects.
In Moco we give it with Atropin (called DuoDote kits), doses are for Mild 600mg, Moderate 1200mg, severe 1800
name the effect. fluids coming out - Rhinorrhea, hypersalivation, diaphoresis, incontinence; also bradycardia and respiratory distress
Muscarinic effects =
name the effect: hypertension, tachycardia, cramping
Nicotinic effects
name the effect: anxiety, coma, less breathing
Central nervous system (CNS) effects
name the effect: Impaired memory, confusion, psychosis
Neuropsychiatric effects =
Alcohol-impacted neurotransmitter
- Gamma-aminobutyric acid (GABA) is impacted by ethanol. It’s the primary inhibitory neurotransmitter. It slows down the brain by blocking signals in the central nervous system.
hernia that leads to opening in diaphragm allowing stomach above diaphragm
Hiatal (hai ei tal) -
Field treatment of GI issues =
- Rule out acute MI (12 lead)
- IV access
- Pain management
- Anti-emetic (zofran)
pain during the menstrual cycle
Dysmenorrhea (dis me Noria) =
= unintentionally caused by medical treatment
Iatrogenic (ai·a·truh·jeh·nuhk)
related to digestion
Peptic =
= tumor/ uncontrolled cell growth
Neoplastic
Vomiting of fresh blood
Hematemesis (hema te masis)
= black tarry stools, suggest upper GI bleed
Melena (muh·lay·nuh)
Passing of red blood from rectum
Hematochezia (hema ta kizya)
, is bleeding from abnormally dilated veins, or varices, that are found throughout the gastrointestinal tract
Variceal (very sil) hemorrhage, aka variceal bleeding
twitching of the corner of the mouth when the facial nerve is tapped in the area of the zygomatic arch.
Chvostek’s sign
Discoloration of the flank, indicates retroperitoneal bleeding.
Grey-Turner’s sign
Pain in the calf upon forced dorsiflexion of the foot. This indicates deep vein thrombosis.
Homan’s sign
Bruising around the belly button.
Cullen’s sign
Increased pain upon applied pressure or inhalation in the subcostal margin of the right upper abdominal quadrant. This indicates gallbladder problems.
Murphy’s sign
Result of stroke, tumor, spinal injury etc. Decreased pupil size, a drooping eyelid and decreased sweating on the affected side of the face.
Horner syndrome
Swollen veins found in the inferior esophagus generally resulting from alcoholism, hepatitis, or any other pathology that can result in hepatic portal hypertension. bright blood since its clean.
Esophagogastric varices
Of the groin
Inguinal
Kidney stones and stones in the urethra
Nephrolithiasis (nefro la THAYA sis) refers to calculi (kal·kyoo·lai) in the kidneys; ureterolithiasis (uritro la THAYA sis) refers to ureteral calculi
A bacterial infection of the kidney
Acute pyelonephritis (pai lo nafRAI tis)
Pain during urination
Dysuria
Marks the upper and lower parts of the GI system. It Extends from the diaphragm to between the duodenum and the jejunum
ligament of Treitz
Involuntary contraction and relaxation of muscles in the digestive tract
Peristalsis
Membrane that attaches the intestine to the abdominal wall and holds it in place
Mesentery
Inflammation of the large intestine, or colon.
Colitis
A condition that causes small, abnormal blood vessels to form in the gut.
Angiodysplasia
The presence of small pouches in the large intestinal (colonic) wall
Diverticulitis (diver ti cue LAI tis)
Suffix itis vs sis
“Itis” means inflammation; “sis” means disease