MEDgems 3 Flashcards
first line treatment for febrile non haemolytic transfusion reaction?
paracetamol
drug given to infants at high risk of RSV - spell it out
pali vi zumab
in x linked scid
are b cells normal?
are t cells normal?
NK cells?
b cells are NORMAL/ raised
low/absent t cell
absent NK
mutation in gamma chain of il2 on xq13.1 so immature b cell and no t /nk
bruton’s x linked hypogammaglobulinaemia
what is b cell?
t cell?
no mature b cell and no circulating after 3 months
t cell normal
John Cunningham Virus causes?
progressive multifocal leukoencephalopathy
what HLA which graves?
HLA-Dr3
SLE HLA?
HLA-DR3
goodpastures HLA?
HLA DR15, DR2
T1DM HLA?
HLA-DR3/DR4
what cytokine is predominant for t cell proliferation?
IL-2
what exists for detection of allergen specific IgE in blood?
Radioallergosorbent test
what is used for diagnosis of type 4?
path testing
what is the vaccine type that uses preformed antigenic proteins?
subunit vaccine - used for viruses
hep b
HPV
what is in a conjugate vaccine?
bacterial polysaccharide
immunogenic toxin
agglutination is?
immunoglobulins bindging to as many pathogens as possible
anti phospholipid syndrome
what autoantibodies?
anti cardiolipin
anti-B2 glycoprotein
Neutralisation is ?
the provess by which a target is covered in autoantibodies
so it can’t enter human cell
Hypersegmented neutrophils are indicative of megaloblastic anemia a condition seen in?
alcoholics
what antibody is secreted in breast milk?
IgA
What is the short-term treatment for severe, life threatening antibody mediated damage
plasmapharesis
what blood product is most commonly associated with bacteria?
platelets
70 year old, kidney failure and haematuria
weight loss
started coughing blood
what immunological condition?
goodpastures
target of p anca?
Myeloperoxidase
what can be given to treat CGD
interferon gamma
