meded lectures path Flashcards
3 stages of TB
primary
latent - gohn focus(this is the central bit of a caseating granuloma) / granuloma forms
secondary - reactvtion due to immunsupression
miliary TB
haemotogenoous spread
how to test for latent TB?
mantoux test
this will be postiive if you have the BCG vaccine
rash assoicated with TB is called ….
lupus vulgaris
side effect of isoniazid ?
peripheral neuropathy (I so numb azid )
give pyridoxine (vit B6)
pyrazinamde side effect ?
hepatitis
thickening of nerves ?
leprasy (M. Leprae)
pathogen for pool owners / sea creatures
M marinarium
pathogen for infective endocarditis for dental procedure
- Poor dental hygiene (Strep. Viridans)
infective endocarditis most common path
staph aureus
infective endocarditis post valvular sugrery ?
staph epidermis (first 2 months)
after 2 months its staph aureus
nausea and vomtiing after a bbq what organism?
depends on timing… if it was immedtaiely then its staph aueus (2-4 hour incubation period)
if its after a while then its the classic campylobacter
organism for travellers diarhheoa ?
e coli
proteus infection associated with what type of kidney stone ?
struvite stones
staghorn calculi
how to manage UTI ?
uncomplicated - 3 day course
male , complicated UTI - 7 day course
use nitrofurentoin / trimethoprim
A complicated UTI is any UTI other than a simple UTI, as defined above. Therefore, all UTIs in immunocompromised patients, males, pregnant patients, and those associated with fevers, stones, sepsis, urinary obstruction, catheters, or involving the kidneys are considered complicated infections.
what do you do for asymptoatic bacteruria ?
do not treat unless pregagnt
(if pregannt avoid trimethoprim in first trimester and avoid nitrofurentoin clsoe to term - can cause haemolysis of newborn)
patients who have a long term catheter are likely to have asymptomatic bacteruira
patient with sickle cell gets osteomyletiis what pathoegn ?
salmonella
if someone has sickle cell its likely to be salmonella
why do you give dexamethasone in meningitis ?
sensorinueral hearing loss
brain abscess in HIV what is it ?
toxoplasmosis
treponema pallidum - what does this pathogen cause ?
syphillis
syphilis tx =
Treatment: Single dose IM Benzathine Penicillin (Doxycycline if allergic)
what pathogen for genital warts ?
HPV
