Med ed revision session: pharmacology Flashcards

1
Q

Potency

A

(ec 50) most potent requires least amount of drug

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2
Q

Efficacy

A

always the highest (max effect the drug can elicit)

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3
Q

Competitive antagonist

A

same shape curve displaced to right

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4
Q

Non comp antagonist

A

drug never reaches max efficacy

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5
Q

Therapeutic index

A

td50 divided by ed 50

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6
Q

first pass metabolism

A

goes through gi tract before bloodstream. this is why oral does higher than iv dose

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7
Q

when need to adjust dose?

A

if have liver failure, low meatabolism more drug in blood stream

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8
Q

% infusion

A

grams per 100 mils

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9
Q

g protein

A

g protein moves activates another protein

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10
Q

steroid hormones

A

have intracellular effect, can go straight to transcription factors

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11
Q

pharmokinetics

A

Pharmacokinetics is the study of the way in which drugs move through the body

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12
Q

pharmodynamics

A

The effect that drugs have on the body

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