Mechanisms Flashcards
propofol mechanism of action
stimulation of GABA α receptors
ketamine mechanism of action
noncompetitive NMDA receptor antagonist that blocks glutamate
thiopental mechanism of action
short-acting barbiturate, activated GABA
etomidate mechanism of action
GABA agonist
dexmedetomidine mechanism of action
highly potent central acting α-2 adrenergic agonist
inhibits release of norepinephrine
decreases cAMP
methohexital mechanism of action
enhances GABA
succinylcholine mechanism of action
binds to 2 alpha subunits of nicotinic cholinergic receptors
allows Na and Ca influx and K efflux
mimics Acetylcholine
neostigmine mechanism of action
inhibits hydrolysis of acetylcholine by AchE
acetylcholinesterase inhibitor
edrophonium mechanism of action
inhibits hydrolysis of Acetylcholine by AchE
physostigmine mechanism of action
inhibits cholinesterase
sugammadex mechanism of action
selective relaxant binding agent that encapsulates roc, vecuronium, or pancuronium
atropine mechanism of action
competitive acetylcholine antagonist at central and peripheral receptors
antimuscarinic, naturally occurring alkaloid
glycopyrrolate mechanism of action
competitive acetylcholine antagonist, synthetic antimuscarinic
scopolamine mechanism of action
competitive antagonist of acetylcholine at muscarinic receptors
ephedrine mechanism of action
sympathomimetic
directly stimulates α-1, β-1, and some β-2
indirectly stimulates endogenous release of norepinephrine or inhibits uptake
phenylephrine mechanism of action
directly stimulates α-1, minimal stimulation of α-2 or β-1 at hight doses
labetalol mechanism of action
nonselective β-1 and β-2 with selective α-1 adrenergic antagonist
considered a β- blocker
esmolol mechanism of action
cardio-selective β-1 antagonist
propranolol mechanism of action
non-selective β-1 and β-2 antagonism
metoprolol mechanism of action
selective β-1 receptor blocker
hydralazine mechanism of action
blocks Ca release from the sarcoplasmic reticulum
metoclopramide mechanism of action
D2 agonist in thechemoreceptor trigger zone
pepcid mechanism of action
H2 receptor antagonist
ondansetron mechanism of action
selective 5-HT3 receptor antagonist
promethazine mechanism of action
phenothiazine, H1 receptor antagonist, anticholinergic action, D2 antagonist in CHEMORECEPTOR TRIGGER ZONE
hydroxizine mechanism of action
blocks acetylcholine in the vestibular apparatus, blocks H1 receptors in the solitary track
oxytocin mechanism of action
indirectly ↑ intracellular Calcium
methylergonovine (Methergine) mechanism of action
semisynthetic ergot alkaloid
arterial vasoconstriction by alpha stimulation
carboprost (Hemabate) mechanism of action
a synthetic analog of prostaglandin F2
cytotec mechanism of action
synthetic prostaglandin E1
mag sulfate mechanism of action
inhibition of acetylcholine release at the neuromuscular junction
labetalol mechanism of action
combined α- and β- antagonist
nipride mechanism of action
potent arteriolar dilator
nitroprusside mechanism of action
venodilator to ↓ cardiac filling
ketorolac mechanism of action
NSAID
non-selective Cox 1 and Cox 2 inhibitor
ofirmev mechanism of action
non -opioid
