MECHANISM: electrophilic substitution Flashcards
1
Q
Give the four nucleophilic additon-elimination reactions for acyl chloride.
A
Acid Chlorides have a strong delta positive carbon which is susceptible to attack from nucleophiles.
Strong delta positive carbon because the oxygen and the chlorine atoms are VERY ELECTRONEGATIVE.
nucleophiles: water, ammonia , alcohols, ch3nh2 (amines)