MDT's Part 1 Flashcards
What is hematuria?
Presence of blood in urine
Gross vs microscopic hematuria?
- Gross: visible to naked eye
- Microscopic: only detectable my microscopy
- Both require further evaluation
Gross hematuria from the lower tract (bladder/urethra) is most commonly found from what?
Urothelial carcinoma of the bladder
What is microscopic hematuria most commonly from?
Benign prostatic hyperplasia
In gross hematuria, what is the presence of blood at the beginning of the urinary stream called and what area of the urinary tract is the source?
- Initial hematuria
- Anterior (penile) urethral source
In gross hematuria, what is the presence of blood at the end of the urinary stream called and what area of the urinary tract is the source?
- Terminal hematuria
- Bladder neck or prostatic urethral source
In gross hematuria, what is the presence of blood throughout the urinary stream called and what area of the urinary tract is the source?
- Total hematuria
- Bladder or upper tract source
When would hematuria indicate Ureteral stone?
Hematuria associated with renal colic
Irritating voiding symptoms in a young woman with hematuria may suggest?
Acute bacterial infection and associated cystitis
In UA for hematuria, what does proteinuria and casts suggest?
Renal origin
Imaging/Referral for hematuria?
- CT scan without contrast of Upper tract
- Cystoscopy
- Urology (anatomic abnormality, urolithiasis, recurrent cystitis)
General considerations for Urinary Tract Infection?
- Coliform bacteria most common (E. coli)
- Ascending infection most common route
- Hematogenous spread to urinary tract is uncommon
- Lymphatic spread is rare
What is acute cystitis?
- Infection of the bladder
- Most commonly due to coliform bacteria (E. coli)
- Uncomplicated cystitis in men is rare and implies pathologic process
S/S of acute cystitis?
- Irritating voiding symptoms
- Suprapubic discomfort (tenderness with palpation)
- Women experience hematuria and Sx’s appear post sex
- Usually afebrile
Imagining for acute cystitis?
- Abdominal ultrasonography or cystoscopy
- CT scan is warranted if pyelonephritis are suspected
Treatment of acute cystitis?
- Women:
- Cipro
- Nitrofurantoin (Macrobid)
- Bactrim
- Men:
- Depends on underlying etiology
- Urinary analgesics
- Pyridium (Phenazopyridine)
Prevention of cystitis in women who have 3 or more episodes in one year?
- Thorough urologic evaluation
- Prophylactic antibiotic therapy
- Bactrim
- Nitrofurantoin
- Cephalexin
- Single dose at bedtime or after intercourse
What is pyelonephritis?
- Infectious inflammatory disease involving kidney parenchyma and renal pelvis
- Gram-negative bacteria most common causative agent
- E. coli
- Proteus
- Pseudomonas
- Infection usually spreads from lower urinary tract (except S. aureus)
S/s of Pyelonephritis?
- Fever
- Flank pain
- Irritative voiding Sx’s
- Shaking chills
- Nausea/vomiting
- Diarrhea
- Tachycardia
Differential Dx for pyelonephritis?
- Acute cystitis
- Acute Intra-abdominal disease
- Males:
- Epididymitis
- Acute prostatitis
Imaging for pyelonephritis?
Renal ultrasound
Inpatient treatment for pyelonephritis?
- Ampicillin IV and gentamicin continued for 24 hours after fever resolved
- Then oral antibiotics to 14 day course of antibiotics
Outpatient treatment for pyelonephritis?
- Ciprofloxacin
- Levofloxacin
- Phenazopyridine