MCQ questions Flashcards
Monocytes move from the systemic circulatory system into general connective tissues, where they differentiate into what cell type?
- Neutrophil
- T-cell
- Macrophage
- B-cell
Macrophage
Which of the following cell types of the innate immune system does not perform phagocytosis?
- Basophils
- Macrophages
- Neutrophils
- Eosinophils
Basophils
Humoral immunity is a type of adaptive immunity that results in the circulation of which of the following throughout the blood?
- Antigens
- Antibodies
- Macrophages
- Natural killer cells
Antibodies
Recognition of self vs. non-self by the adaptive immune system in humans is accomplished in which of the following ways?
- Exposure of T cells to the body’s own antigens in the thymus
- Exposure of T cells to the body’s own antigens in the bone marrow
- Exposure of B cells to the body’s own antigens in the thymus
- Exposure of B cells to the body’s own antigens in the bone marrow
Exposure of T cells to the body’s own antigens in the thymus
Which portion of an antibody provides antigen-binding sites?
- Constant portion
- Heavy chain
- Light chain
- Variable portion
Variable portion
Which of the following is not one of the three main antigen-presenting cell types?
- Macrophages
- B lymphocytes
- Natural killer cells
- Dendritic cells
Natural killer cells
Major histocompatibility complex (MHC) refers to a large group of genes that code for proteins that play an essential role in which of the following?
- Antigen presentation to B lymphocytes
- Antigen presentation to T lymphocytes
- Phagocytosis by neutrophils
- Phagocytosis by macrophages
Antigen presentation to T lymphocytes
The bond that binds light chain and heavy chain in an immunoglobulin is?
- Hydrogen bond
- Hydroxy bond
- Electrostatic bonds
- Disulphide bond
Disulphide bond
Which of following is true?
- leE binds phogocytes
- lgM fixes complement
- lgA binds mast cells
- lgG does not cross placenta
lgM fixes complement
Graft-versus-Host reaction is caused by:
- Complement
- B lymphocytes
- Macrophages
- T lymphocytes
T lymphocytes
Immunocompetent T lymphocytes are selected in the thymus. What is the fate of the T cells that have a high affinity for self-MHC?
- Migration to the peripheral lymphoid organs where they go into apoptosis
- Clonal expansion and migration to the peripheral lymph nodes
- Clonal anergy
- Deletion in the thymus via induction of apoptosis
Deletion in the thymus via induction of apoptosis
Recognition by T cells is a very important tool for any response to a certain antigen. How does the T cell recognise antigen?
- The T cell recognizes antigen via pattern recognition receptors
- The T cell recognizes antigen via the T cell receptor for antigen (TCR), which has a high diversity generated at the level of DNA
- The T cell recognizes antigen via the T cell receptor for antigen (TCR), whereby for every antigen there is already a specific receptor coded at the level of DNA
- The T cell receptor recognizes antigens via the CD3 structure
The T cell recognizes antigen via the T cell receptor for antigen (TCR), which has a high diversity generated at the level of DNA
The primary function of the thymus is:
- Maturation of T lymphocytes
- Production of lymph fluid
- Maturation of B lymphocytes
- Filtration of lymph fluid
Maturation of T lymphocytes
Lymphatic capillaries:
- Are formed from extensions of the capillaries
- Drain extracellular fluid from the tissues
- Function by supplying the tissues with extracellular fluid
- Can be found in all tissues within the body
Drain extracellular fluid from the tissues
Lymphocytes:
- Are only educated in the thymus
- When mature are only found in secondary lymphoid organs
- Enter tissues and remain there for the rest of their lifespan
- Recirculate between blood and lymphoid tissues
Recirculate between blood and lymphoid tissues
