MCQ Flashcards

1
Q

Spontaneous coronary dissection

A

Rare
80% women
Late preganancy, post-partum, perimenopausal often (1/3)
Healthy individuals

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2
Q

Cardiac sarcoidosis

A

May manifest as bradycardia secondary to AV block
Arrythmias may cause sudden death
5-10% symptomatic, with findings in 25%
May cause ventrircular aneurysms

Restrictive cardiomyopathy

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3
Q

Caval filter

A

3rd lumbar vertebra level, infrarenal

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4
Q

Intra-aortic balloon pump

A

Should be located at proximal descending aorta, just beyond origin of left subclavian.

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5
Q

Most common cause of bronchial artery hypertrophy leading to massive haemoptysis

A

Bronchiectasis

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6
Q

Wells score

A
Clinical signs and symptoms
Alternative diagnosis
Tachycardia
Immobilisation or surgery
Previous DVT or PE
Haemoptysis
Malignancy
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7
Q

HOCM

A

The majority of patient show asymmetric septal hypertrophy
Associated with systolic anterior motion of mitral valve, which can cause LVOT obstruction
Tends to cause MR as above, with left atrial enlargementff

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8
Q

Pancoast tumour

A

Syndrome - mass, Horners, shoulder pain, radicular arm pain.

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9
Q

Left atrial enlargement associations

A

Can cause left lower lobe collapse

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10
Q

Takayasu arteritis

A

Most common aortic segment involved is abdominal aorta

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11
Q

Cardiac myxoma

A

Most common benign cardiac mass in adults
Infrequent in children - rhabdomyomas instead
Low T1, variable T2 (some high - myxo)
Heterogeneous enhancement
Arrythmias, dyspnoea, murmur
Solitary in left atrium most common, attached to septum at fossa ovale
Associated with Carneys complex MEN

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12
Q

Bronchiolitis obliterans

A

Bilateral peripheral patchy opacities without zonal distribution
Mosaic perfusion
May have decreased vascular marking and hyperinflation
May be seen in chronic rejection, and graft-v-host disease
Also post infectious. E.g. in CF, or in Swyer-James

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13
Q

Air trapping

A

Most commonly superior segments of lower lobes, or anterior middle lobe or lingula, on expiratory CT

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14
Q

AIP

A

AKA Hamman-Rich
Previously healthy subjects
Diffuse alveolar damage

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15
Q

Infection v lymphoma v kaposi

A

Thalium and gallium scanning
Infection (e.g. PCP) and lymphoma are gallium positive (kaposi not)
Lymphoma and kaposi sarcoma thalium positive
Thalium scanning performed prior to gallium

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16
Q

IPF

A

Can be diagnosed with ATS major and minor criteria in absence of surgical biopsy
Minor: Age > 50 plus symptoms and signs - crackling
Major: absence of alternative on lavage or transbronchial biopsy, exclusion of other causes, UIP on CT

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17
Q

Hodgkin lymphoma, lung

A

10%

Nodules or masses, single or multiple, may cavitate, discrete or indistinct

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18
Q

Best place for PICC

A

Basilic vein

Basilic vein drains ulnar hand. Joins with brachial veins to form axillary vein. Cephalic then joints the axillary vein.

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19
Q

Rebound thymic hyperplasia

A

May occur post chemo

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20
Q

Organising pneumonia

A

Peripheral, lower zone predominant chronic consolidation
Adenopathy in 27%
Effusion in 30%
Atol sign
Non or ex-smokers
Idiopathic, collagen vascular disease, drugs

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21
Q

CPAM

A

25% of congenital lung disease
95% of cystic
1 - 50%
2 - 40%
3 - 10%
Type 2 associated with renal agenesis / dysgenesis, pulmonary sequestration, congenital cardiac disease
No lobar prediliction of sex predominance

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22
Q

Bronchopleural fistula risk factors post pneumonectomy

A
Pre-op radiation
Pre-op uncontrolled infection
Post-op PPV
Faulty closure of stump
Right pneumonectomy - shorter bronchus
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23
Q

Pulmonary infarct stats

A

Only in 10-15% of emboli
Lower lobe 75%
Haemorrhage can occur without infarction

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24
Q

Extralobar sequestration M:F

A

4:1

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25
TB resolution
2/3 no sequelae Ghon focus is calcified granuloma in lungs Ghon complex is above plus lymph node Ranke complex is above but calcified lymph node Calcified lung disease is inactive Or no change for 6 months
26
ARDS
10% have chronic changes in non-dependent lung | Mild chronic fibrosis
27
PIOPED
High probability scan plus high probability clinically is PE confirmed Low probability or normal scan + low clinical probability, PE excluded Otherwise uncertain, and lower limb US or angiography of pulmonary arteries recommended High probability - 2 or more large mismatched defects Intermediate - rest Low - non segmental or subsegmental defects, or matched defects with normal radiograph, or substantially larger radiograph abnormality than perfusion decect Normal - no defect
28
Rasmussen aneurysm
Complication of TB | Pulmonary artery aneurysm adjacent to a tuberulous cavit
29
Lateral CXR
Posterior wall bronchus intermedius / posterior stem line <3mm RUL bronchus above LUL bronchus Left artery superoanterior to bronchus Right artery anterior to bronchus The left pulmonary artery marks superior and posterior contour of hilar complex
30
Earliest asbestos related disease
Pleural effusions, 8-10years post exposure
31
Aortic dissection
Anterior and right lateral wall, just distal to valve, in 65% Transverse or oblique tears, 1-5cm in length with jagged edges Intimal flap detectable in 85-90% Occlusion of coronary arteries in 8% De Bakey - 1 and 2 A, 3 B 1 ascending and descending, 2 ascending only ``` HTN almost invariably Structural abnormalities - bicuspid valve, coarctation, connective tissue e.g. Marfans Turners Pregnancy Balloon pumps ```
32
Libman-Sachs endocarditis
Non-infective, SLE endocarditis Mitral valve (or tricuspid) Intense valvulitis and fibrinoid necrosis Sterile, granular pink vegetations SLE vasculitis can cause pancreatitis, peritonitis, colitis
33
Antiphospholipid syndrome
34% have SLE | Thrombotyic disease, thrombocytopenia, miscarriages
34
RI
PSV - EDV / PSV
35
PI
PSV - EDV / mean V
36
Kasabach-Merritt
Haemangioma causing thrombocytopaenia
37
Endoleak treatment
1 - ASAP repair 2 - If have not stopped spontaneously in 1 month, thrombose 3 - repair with an additional graft
38
Renal artery stenosis
Acceleration time > 0.07 in intrarenal arteries (tardus) Renal aortic ratio >3.5 --> 60% stenosis RI > 0.7 PSV > 180
39
Carotid stenosis
>115 <230 50-69 (ratio 2-4) | >240 >69 (Ratio >4)
40
Renal artery aneurysm
Saccular, non-calcified, occur at bifurcation FMD common cause Female prediliction PAN, IVDU, SLE, RCC, AML, metastatic arterial myxoma, transplant rejection 2/3 extrarenal, 1/3intra
41
FMD
Bilateral renal arteries in 50% Responds well to angioplasty Restenosis 12-25% over 2 years, but HTN doesn't necessarily recur
42
Cardiac MR
Spin echo - black blood Gradient echo - bright blood Gradient echo are flow sensitive Retrospective gating better for diastole
43
Femoral venous catheter
Higher incidence of infection, limit mobility, risk iliac vein stenosis Intended use <30 days
44
Fibrin sheath, tunneled line
Treat with thrombolysis
45
Dural venous sinus thrombosis
Higher risk in puerperium than pregnancy
46
AV fistula stenosis treatment
Angioplasty | Surgery if recurrent or in lower forearm
47
Idiopathic inflammatory AAA
5-25% Fusiform often Delayed enhancement of soft tissue component Dense perianeursymal fibrosis
48
Mycotic aneurysm
2.5% AAA Saccular Perianeurysmal gas, stranding, psoas involvement Staph, salmonella most common
49
Azygous IVC
Associated with polysplenia, dextrocardia
50
Polyarteritis nodosa
Kidneys 70-80% Multiple small aneurysms CNS 10% Most common systemic vasculitis to involve CNS Transmural necrotising vasulitis, fibrinoid necrosis pANCA positive (correlates with disease activity) Good response to treatment Associated with HBV and HIV antigenaemia Males, 5th-7th decade
51
Churg-Strauss
Asthma, hypereosinophilia, systemic small vessel granulomatous necrotising vasculitis May be histo identical to PAN pANCA in 20-70% (Wegeners is cANCA) Renal disease infrequent - heart lungs skin spleen Coronary arteritis and myocarditis
52
Endocardial fibroelastosis
Enlarged left heart and pulmonary venous congestion Restrictive cardiomyopathy Fatal by 2 Endocardial deposition of colagen and elastic tissue
53
Calf vein thrombosis
<5% PE incidence | Propogate in 20%
54
Marantic endocarditis
Non-infective endocarditis Libman Sachs (SLE) or cancer - mucinous adeno of pancreas most common, trauma - catheters Thrombi causing strokes Previous rheumatic fever predisoses
55
Wegeners
Focal necrotising or granulomatous vasculitis cANCA highly specific, correlates with disease activity Cresentic glomerulonephritis Upper and lower respiratory tract
56
Goodpastures
Autoimmune type 2 hypersensitivity to glomerular and alveolar basement membrane
57
Mitral annular calc
Age related - women 60s More common if LV pressure up - HTN, aortic stenosis, HOCM May be a nidus for infective endocarditis, or a focus for thrombus - increased stroke risk Generally does not affect valvular function - rarely does, Associated with mitral regurgitation and conduction defect
58
Lung abscess
Staph, kleb, pseudomonas, proteus | Immunocompromised: candida, leigonella, PCP
59
Plaque on carotid USS
Heterogeneous tends to be unstable | USS bad at detecting intimal flap in dissection - and may be too high to assess
60
Cystic fibrosis
Fibrosing colonopathy usually of ascending colon, complication from excessive doses of pancreatic enzymes Pseudomonas most common respiratory pathogen isolated Survive 40 years Males often infertile Pansinusitis
61
``` Staging cancer, Diaphragm, Parietal pericardial invasion, chest wall, visceral pleural invasion N Satellite nodules Collapse Size ```
``` Diaphragm T4, Parietal pericardium and chest wall (or phrenic nerve) T3 Visceral pleura T2 Same lobe nodule T3 Same lung nodule T4 ``` Ipsilateral hilar N1 Ipsilateral mediastinal and subcarinal N2 Contralateral or supraclav N3 Main bronchus but not carina now T2, carina T4 Atelectasis or obstructive pneumonitis, extending to hilar region T2 <3 1, 3-5 2, 5-7 3, >7 4
62
Klebsiella pneumonia
Prediliction for posterior upper lobe Can cause purulent pericarditis, but staph more common One of the more common causes of empyema (along with strep and staph) Bulging fissures characteristic, but unusual Gram negative
63
Pulmonary amyloid
May cause calcified nodules | Diffuse (alveolar septal), localised nodular, localised tracheobronchial
64
ARDS
Absene of cardiomegaly, pulmonary venous congestion, pleural effusions favour ARDS As does 24 latency of CXR changes May be more peripheral than in hydrostatic oedema Thrombosis may complicate
65
HPOA
Causes identical to clubbing Usually painful Periosteal reaction of diaphysis and metaphysis of distal extremities without underlying bone reaction Tram-track / symmetric linear uptake on bone scan Differential - pachydermoperiostosis - primary POA, with skin thickening also, thyroid acropachy (presentation of autoimmune thyroid disease, almost always with thyroid eye disease), Hypervitaminosis A Chronic venous insufficiency
66
Thymic PET activity
In young female with lymphoma, may be a normal finding before and after treatment
67
Septic emboli
Most commonly IVDU tricuspid endocarditis
68
SLE lung
Pulmonary involvement more common than any other connective tissue disease Pleurisy, pleural disease most common (effusion, thickening) Fibrosis is less common compared with other collagen vascular disease Pulmonary HTN is rare. Can be due to lung disease, or thromboembolism, or may occur similar to primary
69
Myasthenia gravis, thymus
Follicular thymic hyperplasia most common abnormality But also associated with thymoma 10-25% of MG have a thymoma 30-50% of thymomas get MG
70
Benign v malignant thymoma
T1 high in carcinoma, low in benign Can see calcification in both (amorphous, flocculent) Pleural seeding in invasive or malignant SUV cutoff of 5 can give reasonable differentiation on PET for carcinoma v thymoma Thymomas are 50-60 - rare in <20
71
Thymolipoma
Large, fatty, pliable Drapes over heart and vessels Doesn't compress Doesn't invade
72
Mediastinal mass
Most commonly thymic in adults, lymphoma or rebound thymic hyperplasia in kids
73
NF1 lung
Lung disease in 10-20% of adults Upper lobe bullae, basal fibrosis Thoracic meningoceles are on the convex side of the scoliosis
74
Unilateral complete perfusion defect
More common in extrinsic compression than in acute PE
75
Primary, secondary TB
Primary Patchy or lobar consolidation, any lobe, preference for middle and lower lobes Lymphadenopathy (especially in children - 90%, only 10-30% adults. Low density with rim enhancement, usually unilateral) May be miliary (immunocompromised more) Pleural effusions (30-40% adults, 10% children) (so nodes more common in children but effusion more in adults. Adults can present just with lymph nodes [acc to old answers. probably kids can too]) May resolve without any radiological abnormality, or Ghon focus scar may remain (calcified granuloma) Symptoms only in 5% Cavitation uncommon May have massive haemoptysis from erosion into a bronchial artery May have atelectasis in children from compression of airways from lymph nodes. Ghon focus is calcified caseous granuloma in lung Ranke complex is this plus a calcifed node Secondary Apical, cavitates Assman focus
76
Pulmonary hamartoma
Popcorn calc Fat diagnostic 6% of solitary nodules
77
Kaposi sarcoma
Doesn't take up gallium, but does thalium Mid to lower zone, peribronchovascular (and perihilar i.e. cetnral) Strongly enhancing nodes Pleural effusion in 1-2/3. Worse prognosis
78
Pulmonary sling
Aberrant left PA Goes behind trachea, in front of oesophagus Only vascular ring to pass between
79
Atrial septal defect
Less common than VSD Secundum 60-90%, then Primum, 5-20%, then sinus venosus 5%, with unroofed coronary sinus <1% Secundum usually isolated (secundum at fossa ovalis) Primum associated with mitral valve cleft (becomes AVSD) Sinus venosus associated with PAPVR Holt Oram may give secundum ASD, as well as radial ray anomalies (and clavicle hypoplasia) Unroofed coronary sinus associated with left SVC and heterotaxy
80
Pericardial effusion
``` Idiopathic Inflammatory (e.g. Dresslers, collagen vascular disease) Infectious (inc TB) PAH Malignancy Radiotherapy Hypothyroidism ```
81
VSD
Membranous most common (80-90%) | Other types: muscular, inflow, outflor
82
Marfans
AD Ascending aorta aneurysm Aortic incompetence, mitral valve prolapse (myxomatous degeneration of mitral valve) Aortic dissection - cystic medial necrosis Pulmonary artery aneurysms
83
Vascular compression disorders
Eagle syndrome - stylohyoid compresses ICA (CN5,7,9,10 may be involved) Thoracic outlet Nutcracker - L renal vein by SMA Posterior nutcracker - retroaortic L renal vein Median arcuate - Coeliac Popliteal artery entrapment - medial head of gastroc, or popliteus Quadrilateral space syndrome - posterior humeral circumflex, and or axillary nerve. Shoulder pain and paraesthesia Paget-Shroetter (subclavian vein) May-Thurner (Left iliac vein by right iliac artery) Malignant coronary artery Hypothenar hammer Also SMA syndrome (D3), and vascular rings and slings
84
Pulmonary artery aneurysm
``` Trauma Infection e.g. syphilis, TB (Rasmussen) Idiopathic Post valvular dilatation PAH Marfans Vasculitis e.g. Behcets, Takayasu ``` Swan-Ganz catheter placement
85
Lung nodule, risk of malignancy
<7mm, 1% 8-20, 15% >20, 75%
86
Transudate v Exudate
``` Exudate: Protein >30g/L Protein, fluid:serum ratio >0.5 LDH > 20 IU/L LDH, fluid:serum ratio >0.6 ``` Also pH
87
Fleishner guidelines
HR is smoking or other RF (1st degree relative, other exposure) <6mm: LR no FU, HR optional 12m CT 6-8mm: LR 6-12 month, possible 24. HR 6-12 and 18-24 if no change >8mm: 3month CT, PET, or biopsy Multiple 6-8: LR FU 3 month, possibly 24. HR 3 and 24 Multiple >8: LR 3-6 and maybe 24, HR 3-6 and 18-24 Ground glass: no FU if <6, if >6 do 6-12 month and every 2 years Multiple subsolid, 3-6 month and possibly more
88
Bronchial artery embolisation
Particles | Gelatin or PValcohol
89
DVT
Acute thrombus anechoic Chronic echogenic Inspiration increased abdominal pressure and reduces flow, increases diameter (like a valsalva) PEs in 50%
90
PCP
Pleural effusions and lymphadenopathy uncommon May have crazy paving Gallium positive (before xray findings visible) Reticular pattern, perhiliar distribution Subpleural blebs Atypical findings are more common in those on inhaled prophylaxis
91
Fat emboli
Symptoms often transient CT abnormalities last 2 weeks Extent of lung opacification usually reflects severity of disease Can have non-traumatic aetiology e.g. bone infarct, osteomyelitis, acute fatty liver, pancreatitis
92
Amiodarone lung
Pulmonary toxicity in 10% Chronic interstitial pneumonia (includes UIP, NSIP - this most common) Organising pneumonia Diffuse alveolar damage Foamy histiocytes with intracytoplasmic osmiophilic lamellar bodies Peripheral air space opacity, upper lobe predominant, and interstitial fibrosis
93
Methotrexate lung
``` 5% Organising pneumonia Acute interstitial pneumonia Fibrosis Effusions ``` (answers said hypersensitivity pneumonitis, and can have adenopathy)
94
Eosinophilic pneumonia
``` Many drugs: Penicillamine Sulfasalazine Nitrofurantoin NSAIDs Ampicillin Anticonvulsants ACE inhibitors Beta blockers Methotrexate Amiodarone ```
95
Cyclosporine lung
Can cause a solitary pulmonary mass (previous question)
96
Thymic cysts
``` Congenital or acquired Acquired from: Thoracotomy Radiotherapy or chemotherapy for mediastinal tumour Thymic tumours Inflammation May be unilocular or multilocular ```
97
Mesothelioma
May seed along biopsy tract Calc seen in 20%, probably engulfed pleural plaques Predominantly parietal, and to a lesser extent visceral pleura Peritoneal 12-33%, strongly assocaited with asbestos, but 50% have no known exposure. Calc rare.
98
Gallium scan
Positive in infection and lymphoma, not in Kaposi Also in: Sarcoid - pulmonary uptake correlates with disease activity and response to treatment (lambda sign) Amyloid (intense cardiac) Persitant uptake following therapy in Hodgkin lymhoma is a poor prognostic indicator, high risk of recurrence Scan performed 48-72 hours post injection Normal uptake in liver, bone marrow, spleen, salivary glands
99
Hilar adenopathy, drugs
``` Bleomycin Phenytoin (/dilantin) Methotrexate Cyclosporine Carbamazepine Cotrimoxazole Indomethacin Penicillins ``` (not amiodarone or cyclophosphamide)
100
Phenytoin
Can cause eosinophilic lung disease | And hilar adenopathy
101
Bleomycin
A chemotherapy drug SCC of head and neck, cervix, vagina, testicular cancer, Hodgkin lymphoma Organising pneumonia, NSIP, other fibrosis
102
Legionella
SIADH in 15% | Gram negative
103
Pulmonary abscess
``` Staph Klebs Pseudomonas Proteus Immunocompromised: candida, leigonella, PCP ```
104
Pulmonary cavity
``` Strep Staph Haemophilus Other gram negatives (Klebsiella) Anaerobes Aspergillis Legionella (also gram negative) ```
105
Empyema
Chidren - pneumococcus Adults - stap, gram negatives (klebsiella, pseudomonas, haemophilus), anaerobes (usually polymicrobial e.g. bacteroides, actinomyces, clostridium)
106
Empyema necessitans
TB Actinomyces Nocardia
107
Klebsiella
Gram negative Higher incidence in alcoholics and debilitated One of the most common causes of empyema Abscess, effusions Uni/multilocular cavities in 50%, appearing within 4 days Propensity for posterior upper lobe and superior lower lobe Dense lobar consolidation - associated with fissure displacement
108
ABPA
``` Asthmatics Central and upper lobe bronchiectasis Finger in glove Transient consolidation - eosinophilic pneumonia Cavitation in 10% Effusions and adenopathy not a feature ```
109
Hypersensitivity pneumonitis
Can rarely have nodes and effusions Upper zone predominant fibrosis Can have consolidation, ground glass depending on stage of disease
110
Sarcoid
``` ACE has 40% false negative and 10% false positive. May have hypercalcaemia and hypercalcuria Schaumann bodies (laminated calcium containing concretions) (may also be seen in other granulomatous diseases - HSP, beryllosis, uncommonly Crohns and TB) Asteroid bodies (seen in giant cells of granulomas) ```
111
Fibrosing mediastinitis
Encasement and compression of mediastinal structures by fibrosis Histoplasmosis and TB most common cause Can cause pulmonary artery hypertension
112
Histoplasmosis
``` Endemic fungi Can cause calcified granuloma Can cause nodule Can mimic TB Can cause fibrosing mediastinitis ```
113
Thymoma assoications
``` MG Red cell aplasia Hypogammaglobulinaemia SLE RA Non-thymic cancers ```
114
Nodes - hyper, hypodense, and calcified
Hypo: Mets (lung, testis, ovary), lymphoma, infections (inc mycobacterial, fungal), Whipples Hyper: vascular mets (RCC, melanoma, carcinoid, papillary thyroid, Kaposis), castlemans, mild enhancement may be seen in TB, fungal, lymhoma, metastatic lung, sarcoid Calc: treated lymphoma, old granulomas, sarcoid, silicosis, PCP, calcifying mets (BOTOM)
115
Pulmonary hydatid
Second most common organ after liver, most common in children Only coexists with liver disease in 6% Multiple or solitary cystic lesions, uni or bilateral, favous lower lobes.
116
Pulmonary artery hypoplasia
Right > L 3:1, RML then RUL | Associated with bronchiectasis
117
Lung cancer MR
Low to intermediate T1 | High T2
118
Behcets
``` Vasculitis M 2-5x F Mediterranean, middle east, east asia Oral ulceration, genital ulceration, ocular manifestations Aorta and SVC Pulmonary artery aneurysms CNS ```
119
Lung and bone
``` LCH Malignancy TB Fungal disease Other infection Sarcoid Gauchers (rarely involves lungs, resembles DIP) Phakomatoses - TS, NF1 (lower zone fibrosis, upper zone bullae, cor pulmonale) ```
120
Ritalin lung
IV ritalin Causes panlobular emphysema May look like alpha-1-antitrypsin
121
Heroin and Cocaine lung effects
IV heroin can cause pulmonary oedea, haemorrhage, eosinophilic pneumonia IV cocaine can cause pulmonary oedema Crack lung is from smoking crack cocaine Diffuse alveolar damage / alveolar haemorrhage
122
Talc lung
Talcosis - inhalation of talc Pulmonary talc granulomatosis - from injection of tablets intended for oral consumption. Widespread small nodules, may have mid zone prediliction. Coalesce and cause PMF. Talc embolus is often the start of the granulomatosis pathology
123
Alpha-1-antitrypsin
Basal predominant pan-lobular emphysema
124
Metastatic pulmonary calcification
Generally upper lobes. Ground glass nodules Uptake on bone scan is confirmatory Renal failure, HPT, sarcoid, vit D or Ca intoxication, multiple myeloma, massive osteolysis
125
Solo met, septic emboli, met calc zones
Apparently are mostly upper zone (according to a 1987 paper) Apparently septic emboli are predominantly lower lobe. Metastatic calc is predominantly upper.
126
Pulmonary alveolar microlithiasis
Mid to lower zone predominant. Sand like calc in the lungs Calcium phosphate microliths Young adults
127
Endobronchial metastases
RCC, thyroid, melanoma Breast Colorectal Cervical
128
Cannonball mets
Kidney, choriocarcinoma | Less commonly, prostate, endometrial, synovial sarc
129
Lymphangitic carcinomatosis
``` Breast Lung Colon Stomach Prostate Cervical Thyroid ```
130
Pleural mets
``` Lung Breast Ovarian Lymphoma Gastric Invasive thymoma ```