mcp: contra Flashcards
OC MOA
comprised of synthetic hormones (estrogen, progesterone) that inhibit ovulation via negative feedback of the HPG axis
estrogen-like hormones
- Suppress FSH release
- Inhibit follicle maturation
progesterone-like hormones
- Suppress LH surge
- Thickens cervical mucus
- Induces endometrial atrophy
- Prevents ovulation and implantation
synthetic estrogen in combined OCs is usually
ethinyl estradiol
synthetic progesterone in combined OCs may be
Levonorgesterol
Norethindrone
Norgestimate
Drospirenone
synthetic progesterone in POPs may be
Norethindrone
Norgestrel
(lower dose)
estrogen side effects
-N/V
-breast tenderness
-water retention
-spotting
-migraines
-cyclic weight gain
(leaky, swelling boobs w/a headache)
progesterone side effects
-N/V
-acne
-incr appetite
-weight gain
-depression
-hair loss
-vaginal candidiasis
(aging teen)
OC beneficial effects
- Regulates menstrual cycles in patients with dysmenorrhea
- Reduces risk for endometrial and ovarian cancer