MCM Supplament Flashcards
1
Q
What does P53 do
A
Stops cell cycle
2
Q
What pushes the cell cycle forward
A
Cylins bound with CDK
3
Q
Left shift means what
A
Increased affinity, polycythemia
4
Q
Right shift means what
A
Decreased affinity, anemia
5
Q
Chocolate blood
A
Methemoglobinemia
6
Q
Oxygen capacity
A
Hemoglobin x 1.34
7
Q
Oxygen content
A
Capacity x percent
8
Q
Primary polycythemia
A
BM makes RBCs without being told to
9
Q
Secondaey polycythemia
A
BM is ok, but kidneys arent getting oxygen and tell BM to make more RBC
10
Q
Increase in HIF means what
A
Decrease in ubiquination, and increase in transcription factor of EPO transferoportin
11
Q
Low Iron means what
A
Microcytic, hypochromic anemia
12
Q
Autosomal dominant progression
A
Father to son direct transfer
13
Q
X-linked recessive transfer
A
Only males affected
14
Q
What does rifampin do
A
Inhibition of RNA synthesis
