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Virology > MCF > Flashcards

MCF Flashcards

1
Q

What is Malignant catarrhal fever (MCF)

A
  • A sporadic, usually fatal, multisystemic viral disease of cattle, deer, bison, and certain exotic ruminants
  • characterized in cattle by profuse mucopurulent nasal and ocular discharges, keratoconjunctivitis with corneal opacity, and enlargement of peripheral ln
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2
Q

Taxonomy of MCFV?

A
  • Family: Herpesviridae
  • Subfamily: gammaherpesvirinae
  • Genus: Macavirus
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3
Q

What are the characteristics of MCFV?

A
  • dsDNA genome
  • Enveloped
  • Icosahedral symmetry
  • cause lymphoproliferative disease (gamma-herpesviruses)
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4
Q

What are the subgroups of MCF and their hosts?

A
  • OvHV-2 - sheep
  • AIHV-1 - Wildebeest
  • AIHV-2 - Hartebeest, topi
  • CpHV-2 - Goat
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5
Q

What is the history of MCF?

A
  • Known in cattle in africa for centuries
  • Sheep associated form occurs world-wide
  • First reports of MCF-like disease in US cattle dates back to 1920s
  • First bison case in US reported in 1873
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6
Q

What species are affected by MCF?

A
  • Domestic cattle
  • American Bison
  • Several species of Cervidae
  • Buffalo
  • Several wildlife ruminants
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7
Q

How is MCF transmitted?

A
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8
Q

How does MCF transmission occur in carrier species?

A
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9
Q

How is MCF transmitted in susceptible species?

A
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10
Q

What is the Incubation period, morbidity, mortality and duration of MCF?

A
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11
Q

What is the pathogenesis of MCF

A
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12
Q

WHat are the clinical signs of MCF

A
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13
Q

What gross lesions are common to MCF

A
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14
Q

What are the different forms of MCF?

A
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15
Q

What happens in the peracute and Head and eye forms of MCF?

A
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16
Q

What are the Intestinal and Mild forms of MCF like?

A
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17
Q

How is MCF diagnosed?

A
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18
Q

What serology tests are available for MCF

A
  • Virus neutralization (VN)
  • Immunobloting
  • ELISA 9cELISA)
  • IFA
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19
Q

What samples should be taken for histopathology in MCF?

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20
Q

What are common microscopic lesions with MCF?

A
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21
Q

What is needed for PCR for MCF

A
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22
Q

What is needed for Virus Isolation diagnosis of MCF?

A
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23
Q

What are the differential dx for MCF in cattle?

A
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24
Q

DDx for MCF in cervids?

A
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25
Q

How can MCF (AIHV-1) be controlled?

26
Q

What are the important points of MCF

27
Q

Clinical definition of Rinderpest?

28
Q

Family and genus of Rinderpest?

29
Q

What is the relatedness of Morbilliviruses

30
Q

How long has Rinderpest been around?

31
Q

What are the recent events with Rinderpest

32
Q

How was Rinderpest eradicated

33
Q

What are the characteristics of the Rinderpest Viruse

34
Q

What are the characteristic of Rinderpest infection?

35
Q

How is Rinderpest transmitted?

36
Q

What animals host Rinderpest?

A
  • Pigs
    • asiatic pigs are highly susceptible & spread the disease
    • European breeds develop mild transient virus
  • African & asian game:
    • Wide sprectrum of clinical disease
    • African buffalo, Giraffe & Kudu: very sensitive
    • Wild Asian buffalo: very severe
37
Q

What are the clinical stages of the Classic Form of Rinderpest?

A
  • Incubation period = 4-5d (range of 3-15)
  • Febrile Period: 104-107F
    • Depression, anorexia, decreased rumination, increased respiratory & heart rate
38
Q

What are the post-mortem lesions seen with Rinderpest?

39
Q

What is Tiger/Zebra striping of Rinderpest?

40
Q

How is Rinderpest Diagnosed in the field? What samples should be taken for the lab? Where can the virus be isolated from?

41
Q

What are the diagnostic test options for Rinderpest?

42
Q

What are the differential diagnosis for Rinderpest

43
Q

How is Rinderpest prevented and Controlled?

44
Q

What is the vaccine for Rinderpest

45
Q

What are the important points of Riderpest?

46
Q

What is Bovine Papillomavirus?

47
Q

What is the pathogenesis for Bovine Papillomatiosis?

48
Q

How is Bovine Cutaneous papillomatosis dx?

49
Q

How is Bovine Cutaneous papillomatosis prevented/controlled?

50
Q

What is Bovine Ulcerative mammillitis?

51
Q

What is the pathogenesis for Bovine ulcerative mammillitis?

A
  • Scab forms
  • Lesions heal 3-4 weeks
  • Nursing calves get lesions on the face and muzzle
52
Q

How is Bovine ulcerative Mammillitis diagnosed?

53
Q

How is Bovine ulcerative Mammillitis controlled?

54
Q

What is Cowpox & Bovine Vaccinia Mammillitis?

55
Q

What is the structure of Cowpox & Bovine Vaccinia Mammillitis?

56
Q

What is the pathogenesis of Cowpox & Bovine Vaccinia Mammillitis?

57
Q

How is Cowpox & Bovine Vaccinia Mammillitis diagnosed?

58
Q

What is Pseudo-cowpox (PCP)?

A

Cause regressing “ring” sores

59
Q

How is PCP diagnosed?

60
Q

What is Milkers Nodules?

61
Q

What is Bovine Papular Stomatitis (BPS)

62
Q

How is BPS diagnosed?

Virology (37 decks)

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