MCC Page 6 & 7 Flashcards
Associated with Low Cardiac risk
Frederickson Classification of hyperlipidemia
Type I Hyperchylomicronemia
Type IV Familial Hypertriglycidemia
Type V Hyperlipoproteinemia
I LOVE HEART (1,4,5)
Associated with High Cardiac Risk
Frederickson Classification of hyperlipidemia
Type II a Familial Hypercholesterolemia
Type II b Mixed Defect - Familial combined dyslipidemia
Eruptive & Palmar Xanthomas
Frederickson Classification of hyperlipidemia
Type III Familial Dysbetalipoproteinemia
Associated with high cardiac risk, Xanthelasma, Tendon Xanthoma, Corneal Arcus, Hypothyroidism, & Nephrotic Syndrome
Frederickson Classification of hyperlipidemia
Type IIa Familial Hypercholesterolemia
TAG: <200 mg/dL
Clear, Hazy/Turbid, Lactescent, Opaque/Milky
Clear
TAG: >300 mg/dL
Clear, Hazy/Turbid, Lactescent, Opaque/Milky
Hazy/Turbid
TAG: >400 mg/dL
Clear, Hazy/Turbid, Lactescent, Opaque/Milky
Lactascent
TAG: >600 mg/dL
Clear, Hazy/Turbid, Lactescent, Opaque/Milky
Opaque/Milky
A positive acute phase reactant that increases up to 1000x during an infection
Protein
Serum Amyloid, C reactive protein
Significantly contributes to plasma oncotic pressure
Protein
Albumin
Marker for Nutritional Status
Protein
Pre-albumin
Decreased in Down Syndrome
Protein
AFP
Binds and activates PSA and is increased in Alzheimer’s disease, Neonatal Bacterial Meningitis
Protein
AAT
Largest Major nonimmunoglobulin protein
Protein
AMG
Binds free HEMOGLOBIN through the Alpa Chain
Protein
Haptoglobin
Decreased in Wilson’s disease
Protein
Ceruloplasmin
Binds to free HEME
Protein
Hemopexin
Marker for congestive heart failure
Protein
B-Natriuretic Peptide
A glycoprotein composed of two nearly identical subunits. Variants demonstrates a wide variety of cellular interactions: Cell adhesion, Tx differentiation, growth and wound healing
Protein
Fibronectin
___________ is a glycoprotein used to aid in predicting the short-term risk of premature delivery
Protein
Fetal fibronectin
This protein shows an inverse correlation with BMI. Lower levels of this protein correlate with an increased risk of heart disease, type 2 diabetes, and metabolic syndrome
Protein
Adiponectin
This is an accurate marker of CSF leakage
Beta-trace protein
This protein is a biochemical marker of bone resorption that can be detected both in serum & urine
Protein
Cross linked telopeptide (CTX)
These are proteolytic fragments of collagen I formed during bone resorption
Recently proposed new marker for the early assessment of changes to the glomerular filtration rate
Protein
Cystatin C
Cystatin C is produced and destroyed at a constant rate hence..
Amyloid stains with _______
Congo red
This protein can be used as a supplemental tests to help differentiate a diagnosis of Alzheimer disease from other forms of dimentia
Due to the reason that this is increased in patients with Alzheimer’s disease
Amyloid
This is a product of protein and amino acid metabolism
NPN
Urea
This is a product of protein and amino acid metabolism
NPN
Urea
Product of creatinine metabolism by muscles
NPN
Creatinine
Product of catabolism of purine Nucleic Acid
NPN
Uric Acid
Earliest biomarker for acute kidney injury
Neutrophil gelatinase-associated lipocalin
Standard reference method for Protein
Kjehl-Dahl
Most widely used method for Total protein determination
Biuret
