MCC page 4-5

Question 1

Normal values for Total Cholesterol, LDL Cholesterol & TAG

Answer 1

Total Cholesterol: <200 mg/dL

LDL Cholesterol: <100 mg/dL

TAG: <150 mg/dL

Question 2

Highest Values for Total cholesterol, LDL, & TAG

Answer 2

Total Chole: >240 mg/dL
LDL: >190 mg/dL
TAG: >500 mg/dL

Question 3

There are 3

One step method for cholesterol determination

Only Colorimetry is performed

Answer 3

Pearson, Stearn, & Mc Gavack

Question 4

Two step method for Cholesterol determination

Extraction + Colorimetry

Answer 4

Bloor’s

Question 5

Three step method for Cholesterol determination

Saponification + E + C

Answer 5

Abell-Kendall

Question 6

Extracting agent in Abell-Kendall method

Answer 6

Petroleum Jelly

Question 7

Four step method of Cholesterol determination

S + E + C + Precipitation

Answer 7

Schoenheimer, Sperry, Parekh, & Jung

Question 8

Friedelwald Equation for LDL Determination

Answer 8

LDL (mg/dL) = Total Chole - HDL - TAG/5

LDL (mmol/L) = Total Chole - HDL - TAG/2.5

Question 9

Delong’s equation for LDL determination

Answer 9

LDL (mg/dL) = TC - HDL - TAG/6.5

LDL (mmol/L) = TC - HDL - TAG/2.825

Question 10

Friedelwald equation is not applicable when TAG reaches _______

Answer 10

> 400 mg/dL

Question 11

Major Lipoproteins

Answer 11

CM, LDL, VLDL, & HDL

Question 12

Minor Lipoproteins

Answer 12

IDL, Lp(a)

Question 13

Abnormal Lipoprotein

Answer 13

LP(x), B-VLDL

Question 14

Other name for LDL

Answer 14

Beta Lipoprotein

Question 15

Other name for VLDL

Answer 15

Pre-Beta Lipoprotein

Question 16

Other name for HDL

Answer 16

Alpha Lipoprotein

Question 17

Also known as sinking pre-beta lipoprotein

Answer 17

Lp(a)

Question 18

Also known as Floating Beta Lipoprotein

Answer 18

B-VLDL

Question 19

What is the most Atherogenic Lipid

Answer 19

1st: Cholesterol
2nd: TAG

Question 20

What is the most Atherogenic Lipoprotein

Answer 20

1st: LDL
2nd: VLDL

Question 21

Lipoprotein that contains the highest percent of phospholipid

Answer 21

HDL

Question 22

Known as the Non-atherogenic Lipoprotein

Answer 22

Chylomicron

Question 23

Known as the Reverse atherogenic Lipoprotein

Answer 23

HDL

Question 24

Lipoprotein with the lowest Cholesterol content

Answer 24

LDL

Question 25

Standing Plasma Test is for

Answer 25

CM

Question 26

Reason for the creamy layer on top of samples

Answer 26

CM

Question 27

Reason for Turbid Plasma

Answer 27

VLDL

Question 28

HDL content that is a negative risk for coronary heart disease

Answer 28

> 60mg/dL

Question 29

HDL content that is a positive risk for CHD

Answer 29

<40 mg/dL

Question 30

Activates LCAT & is the major lipoprotein in HDL

Answer 30

Apo-A1

Question 31

Major LPP in VLDL & LDL

Answer 31

Apo B 100

Question 32

Majoy LPP in CM

Answer 32

Apo B 48

Question 33

Activates Lipoprotein Lipase

Answer 33

Apo C-II

Question 34

Associated with Type 3 Hyperlipoproteinemia

Answer 34

Apo E II

Question 35

Associated with high LDL; Higher risk for CHD & ALZHEIMER’s disease

Answer 35

Apo E-IV

Question 36

Bassen-Kornzweig is also known as

Answer 36

Abetalipoproteinemia

Question 37

Sphingomyelinase Deficiency

Answer 37

Neimann-Pick Disease

Question 38

HDL deficiency

Answer 38

Tangier’s disease

Question 39

LCAT deficiency

Answer 39

Fish eye’s disease

Question 40

LPL deficiency

Answer 40

Chylomicronemia

Question 41

Hexosaminidase A deficiency

Answer 41

Tay-sach’s disease

Question 42

Hexosaminidase A & B deficiency

Answer 42

Sanhoff’s disease