Maternal Recognition of Pregnancy Flashcards
Luteolysis
Functional lifespan of the CL is terminated in the non-fertile cycle
Formation of the CL
Formed from granulosa and theca cells of the ruptured follicle following ovulation.
Granulosa cells post luteinization
Large luteal cells
Theca cells post luteinization
Small luteal cells
CL main function
Secrete hormone progesterone under the control of the pituitary peptide hormone, LH
Conceptus
An early embryo. Fetus and placenta combines
Cow MRP factor
bIFN tau
Ewe MRP factor
oIFN tau
Sow MRP factor
Estradiol-17b
Mare MRP factor
3 proteins/unknown
Queen MRP factor
PRL?
Bitch MRP factor
None needed
Endometrial cups
Source of eCG and a placenta-associated structure. Increase immunological tolerance of the mare to protect the fetus.
Formation of eCG
Alpha and Beta chain
Woman luteal regression
14
Cow luteal regression
18
Ewe luteal regression
14
Sow luteal regression
16
Mare luteal regression
15
Luteal Regression Feedback Loop
Positive feedback related to the oxytocin amount
What does CL progesterone do?
Converts proliferative endometrium to secretory endometrium. Prohibits spontaneous smooth muscle contractions.
Definition of eCG
Equine chorionic gonadotropin
eCG vs LH
eCH is a highly glycosylated form of LH with a long half life
Half life of eCG
6 days
Why don’t bitches need a MRP factor?
Because the CL lifespan is so long
