Maternal Physio - GIT Flashcards
Organs displaced upward by the enlarging uterus
The stomach, appendix, and intestines
Appendix position and implication
- Displaced upward and laterally
- Pain from appendicitis may occur much higher in the abdomen because the gravid uterus pushes the appendix up
Gastric emptying time
- During pregnancy
- During labor
- During pregnancy
- Unchanged
- During labor
- Prolonged during labor and administration of analgesic agents
Gum changes
- May be hyperemic and softened
- Epulis of pregnancy
- focal, highly vascular swelling of gums but regresses spontaneously after delivery
Effects of progesterone in GIT
- ↓ lower esophageal sphincter tone → heartburn
- ↓ bowel peristalsis → constipation → hemorrhoids
Memory aid:
-
Progesterone has a somehow relaxing effect
- Relaxed ES tone
- Relaxed bowel → ↓ bowel peristalsis
Mechanism for hemorrhoid development
Constipation and elevated pressure in veins below the level of the uterus
Liver enzyme(s) with increased activity
- Alkaline phosphatase activity in serum almost doubles during pregnancy
- Total albumin
- Serum globin
Liver enzyme(s) with decreased activity
- ALT
- AST
- GGT
- Bilirubin
- Serum albumin
Albumin levels in pregnancy
Serum albumin ↓, but total albumin ↑ because of a greater volume of distribution
Liver size in pregnancy
Remains the same
Why are pregnant women prone to cholestasis?
- Progesterone inhibits CCK-mediated smooth muscle stimulation → impairs gallbladder contraction → increased residual volume and cholestasis
- Estrogen inhibits intraductal transport of bile acids → contributes to cholestasis
- Memory aid:*
- Progesterone – relaxing effect – inhibits CCK – impaired GB contraction
Cholestasis with increased lipids and cholesterol leads to
Higher incidence of gallstones, cholecystitis, and biliary obstruction