Maternal Medicine (pre-existing illness) Flashcards
What anti-epileptics should pregnant ladies avoid?
Sodium valproate, carbamazepine, phenytoin - TERATOGENIC (neural tube defects), vitamin K deficiency
How much folic acid should diabetics and epileptics take?
5mg, for at least 12 weeks before conception and continue until delivery
Should a lady change her medication for epilepsy during pregnancy?
CASE BY CASE APPROACH - any change should be undertaken before conception, and given a trial run
How will a diabetic’s insulin requirement change during pregnancy?
The insulin dose should be increased to counteract diabetogenic hormones that are produced during pregnancy
What is the risk to the newborn infant, if the mother is diabetic?
Neonatal hypoglycaemia - early feeding and regular blood glucose monitoring should be preformed to minimise this risk, as it can lead to cerebral damage if left untreated.
What BM levels should be targeted during pregnancy?
<5.5 pre-meal
<7.0 2 hours after a meal
What BM levels should be targeted in the puerperium?
4-9mmol/L
When should T1/2DM patients give birth?
Induction of labour at 38-39 weeks
Why is anaemia common in pregnancy?
There is an increase in blood volume during pregnancy, which is higher than the increase in red cell mass, causing a subsequent decrease in haemoglobin concentrations. Iron and folic acid requirements increase.
How can iron-deficiency anaemia be treated?
- Oral iron tablets
- Ferrous sulphate challenge
- Blood transfusion
When in pregnancy is haemoglobin checked?
Booking, 28, 34 weeks
What level should Hb be above ideally?
105
What are the risks of anaemia to pregnancy?
Preterm labour
PPH
What are the maternal risks of Diabetes in pregnancy?
- Pre-eclampsia
- Miscarriage
- Diabetic retinopathy
- Preterm labour
- Nephropathy
What are the foetal risks of Diabetes in pregnancy?
- Preterm labour/prematurity
- Macrosomia
- Congenital abnormalities
- Birth injury
- IUD
- Increased perinatal mortality