Maternal Medicine Flashcards

1
Q

How many times greater is the risk of fetal malformations when a patient is on anti-TBF drugs?

A

Similar to general population

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2
Q

What proportion of patients with MG have a) remission, b) same, c) worsening of symptoms during pregnancy?

A

a) 30%
b) 30%
c) 40%

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3
Q

What is the risk of PET for previous
a) PET, b) with birth 28-34/40,
c) with birth 34-37/40

A

a) 16%
b) 33%
c) 23%

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4
Q

What proportion of women with asthma have a) worsening, b) improving, c) same symptoms in pregnancy?

A

All 33%

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5
Q

What special measures need to be taken for flight in pregnancy with BMI >35?

A

LMWH

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6
Q

What special measures need to be taken for flight with twin pregnancy?

A

Don’t fly beyond 32/40
TEDS if > 4 hours

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7
Q

What is the most common benign liver tumour?

A

Hepatic haemangioma

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8
Q

What are the risks of vertical transmission of parvovirus, a) < 15/40, b) 15-20/40, c) at term

A

a) 15%
b) 25%
c) 70%

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9
Q

What are the contraindications to cabergoline?

A
  1. Pre-eclampsia
  2. Cardiac valvulopathy
  3. Hx of pericardial fibrotic disorders
  4. Hx of pulmonary fibrotic disorders
  5. Hx of retroperitoneal fibrotic disorders
  6. Hx of puerperal psychosis
  7. Hypersensitivity to ergot alkaloids
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10
Q

What is an acceptable value of factors VIII & IX pre-procedure?

A

0.5

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11
Q

When is red cell exchange transfusion indicated

A

After RBC transfusion of >1 unit

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12
Q

What dose of anti-D is needed if D +ve platelets (up to 5 units) are given to D -ve women?

A

250 units

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13
Q

How does vasa praevia typically present?

A

Fresh PV bleeding at the time of ROM with fetal decelerations

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14
Q

What are the recurrence rates of placental abruption?

A

After 1, 4.4%
After 2, 19-25%

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15
Q

What is the biggest risk factor for developing hepatic adenoma?

A

COCP

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16
Q

How often should anti-D be given with recurrent PV bleeding?

A

6-weekly intervals

17
Q

What is the incidence of focal nodular hyperplasia?

A

3%

18
Q

What proportion of successful IVF results in twin pregnancy?

A

24%

19
Q

What proportion of twin pregnancies deliver before 37/40?

A

50%

20
Q

How does the perinatal mortality of twins compare to singletons?

A

3x greater

21
Q

What is the incidence of hypertensive disorder in pregnancy?

A

8-10%

22
Q

What proportion of patients with acute fatty liver of pregnancy a) have renal impairment & b) require renal replacement?

A

a) 14%
b) 3.5%

23
Q

What is the risk of malignant transformation of hepatic adenomas?

A

5%

24
Q

What proportion of patients with acute fatty liver of pregnancy develop renal impairment?

A

14%

25
Q

What is the incidence of diabetes insipidus in pregnancy?

A

2-4:100,000

26
Q

What are the minor risk factors for SGA?

A
  1. Age 35+
  2. IVF singleton
  3. Nulliparity
  4. BMI <20
  5. BMI 25-34.9
  6. Smoker 1-10/day
  7. Low fruit intake
  8. Previous PET
  9. Pregnancy interval < 6 months
  10. Pregnancy interval > 60 months
27
Q

What action should be taken for 3+ minor SGA risk factors

A

UA Doppler 20-24/40
If normal, growth & UA 3rd trimester
If abnormal, serial growth & Doppler from 26-28/40

28
Q

What are the major risk factors for SGA?

A
  1. Age >40
  2. Paternal SGA
  3. Maternal SGA
  4. Cocaine use
  5. Daily vigorous exercise
  6. Previous SGA baby
  7. Smoker > 10/day
  8. Chronic HTN
  9. Diabetic vascular disease
  10. Renal impairment
  11. Antiphospholipid syndrome
  12. Heavy PVB
  13. PAPP-A <0.4 MoM
29
Q

What action should be taken for 1+ major risk factors for SGA?

A

Serial growth & Dopplers from 26-28/40

30
Q

What is the current rate of TB in pregnancy in the UK?

A

4 per 100,000

31
Q

When should infliximab be stopped in pregnancy?

A

16/40

32
Q

What is the global incidence of conjoined twins?

A

1 in 100,000