Massive PE Flashcards

1
Q

What is a massive PE?

A

Massive pulmonary embolism is defined as obstruction of the pulmonary arterial tree that exceeds 50% of the cross-sectional area, causing acute and severe cardiopulmonary failure from right ventricular overload.

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2
Q

Meds for massive PE

A

Enoxaparin (lovenox)
Heparin (UF)
tPA (tissue plasminogen activator)

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3
Q

Enoxaparin (lovenox) dose (massive PE)

A

1mg/kg SQ

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4
Q

Heparin (UF) dose (massive PE)

A

80 U/kg bolus (no max)
Then
18 U/kg/kr drip

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5
Q

tPA dose (massive PE)

A

100mg (10mg over 10 min then 90mg over 2 hrs)

if PE is susptected cause of cardiac arrest:
- 50mg over 2 min
- continue CPR x 15 min and repeat PRN

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