Mass Transport Flashcards
What are fats broken down into
Fatty acids and monoglycerides
What are proteins broken into
Amino acids
Digestion
Process by which larger molecules are hydrolysed to smaller molecules that can be absorbed across cell membranes
Amylase
Breaks down carbohydrates
Catalyses conversion of starch into maltose by hydrolysing glycosidic bonds
Produced by salivary glands
Membrane bound dissacharides are enzymes that attach to membrane of epithelial cell lining break down dissacharides
Membrane bound dissachridases
Enzymes that are attached to cell memebrane of epithelial cell lining the ileum
Break down dissacharides into monosaccharides
Lipase
Catalyse break down of lipids into monoglycerides and fatty acids by hydrolysing Ester bonds
Made in Pancreas and in small intestine
Fats and oils broken down into micelles by biles salts by emulsification
Triglycerides broken down into monoglycerides
Endopeptidases
Hydrolysed peptide bonds in central region of protein forming series of peptide molecules
Trypsin and chymotrypsin produced by pancreas then in small intestine
Pepsin works in acidic conditions
Exopeptidases
Hydrolysed peptide binds I’m terminal amino acids of the peptide molecules formed by endopeptidases. They remove single amino acids
Dipeptidasea
Hydrolyse bonds between amino acids of a peptide. Part of cell surface membrane of epithelial cells lining the ileum
Haemoglobin
Large protein with a quarternary structure of 4 chains
Haemoglobin Structure
Large protein with quarternary structure with 4 polypeptide chains
Each chain has haem group with contains iron ion (gives red colour)
Can carry 4 oxygen molecules at once
High affinity
High attractive force
Readily associates with O2
Low affinity
Lower association with oxygen but readily dissociates
Low partial pressure
Hb has a low affinity for oxygen therefore readily dissociates meaning low saturation
Bohr effect
Cells respire raising the pCO2
This increases oxygen unloading rate shifting the curve right
Saturation of blood with O2 lower for given pO2 meaning more oxygen released
Loading
CO2 is constantly being removed so there’s a lower concentration so pH is raised
The shape of the protein changes and the affinity of haemoglobin increases
Active animals
Have lower affinity
Vena cava
Carries deoxygenated blood to the heart
Aorta
Carries oxygenated blood to the body
Pulmonary artery
Carries deoxygenated bloody to the lungs
Artery
Carry oxygenated blood from the heart to the rest of the body
Thick muscular walls prevent bursting
Elastics tissues to stretch and recoil during pumping to maintain pressure
Pulmonary artery carries deoxygenated blood to lungs
Veins
Carry deoxygenated bloody back to the heart under low pressure
Have wide lumen but little muscle or elastic
Have valves to prevent back flow
Blood flow helped by contractions is body muscles surrounding
Pulmonary veins carry oxygenated blood from lungs to heart
Capillary
Walls have thin lining layer for short diffusion path way
Large SA for exchange
Narrow diameter for short diffusion pathway
Narrow lumen so RBC squeezes against capillaries
Have spaces between lining so WBCs can escape to deal with infection
Tissue fluid formation
At start if capillary bed the hydrostatic pressure inside capillaries greater than tissue fluid so fluid pushed out into spaces around the cells
Hydrostatic pressure in capillaries reduces lower and Venule end of bed
Increase in plasma protein at venule end the WP is Lower than tissue fluid
Water re-enters capillaries at venule end via osmosis