DNA RNA And Protein Synthesis Flashcards
What’s the dna molecules wound around
Histones (help support DNA)
Eukaryotic DNA
Contain linear DNA molecules existing as chromosomes
Wound around histones to fit in nucleus (cooled tightly to make compact)
Prokaryotic DNA
DNA molecules short and circular
Not wound around histones
Free floating in cytoplasm
Condenses by supercoiling
Gene
A sequence of DNA bases that codes for either a polypeptide or functional RNA
Genome
Complete set of genes in the cell
Proteome
Full range of proteins that the cell is able to produce
Intron
Section of gene that codes for polypeptide that doesn’t code for amino acids
Removed during protein synthesis
Exon
All the bits that do code for amino acids
Allele
Different forms of a gene
mRNA
Made during transcription
Carries genetic code from DNA to ribosomes where used to make protein during translation
Single strand polynucleotide
tRNA
Involved in translation
Carries amino acids that used to make proteins to ribosomes
Single polynucleotide strand that’s folded into clover shape due to hydrogen bonds
Has specific base sequence at one end called anticodon
Have amino acid binding site
Transcription
RNA polymerase attaches to double helix
Hydrogen bonds between double helix break by hydrolysis (uncoils)
RNA lines up free RNA nucleotides with exposed bases on template
Complementary strands on DNA joined to RNA nucleotides by condensation in presence of RNA polymerase
RNA polymerase moves along DNA separting strands and assembling mRNA strand
Hydrogen bonds reform once RNA polymerase passed
RNA detaches when teaches stop signal
Splicing
When introns are removed and functional exons are joined together
Translation
mRNA attaches to ribosome snd tRNA molecules carry amino acid to it (ATP provides energy for hydrogen bond between tRNA and amino acid)
tRNA carrying amino acid with anticodon complementary to first codon attaches to mRNA
Second molecule attaches and the 2 amino acids joined by peptide bond and first codon moves away
Meiosis
DNA unravels and replicated to form chromatids
DNA condenses to form double armed chromosomes and nuclear envelop breaks down
Spindle fibres form and chromosomes arrange in homologous pairs
Spindle fibres contract pulling chromosomes to opposite poles
Nuclear envelope form 2 diploid daughter cells