Mass Spectrometry

Question 1

name the four processes of mass spectrometry

Answer 1

1. sample into gas phase: A(1) + B(s) + C(g)
2. ionise A+(g) + B+(g) C+(g)
3. mass selection B+
4. detection number of B+ ions

Question 2

what are the three types of sampling methods in mass spectrometry?

Answer 2

gas, liquids, solids

Question 3

how is gas measured?

Answer 3

injected directly into a vaccum

Question 4

how are liquids analysed with mass spectrometry? three steps

Answer 4

when you spray the liquid into a vaccum using a charged nozzle.

the droplets break up and the solvents evaporate

molecules then become charged - so dont need to seperate as the ionise step

Question 5

how are solids measured with mass spectrometry?

Answer 5

use a plasma to ablate (to remove or dissipate by melting etc) molecules off the surface. molecules become charged so dont need a secondary ionisation step

Question 6

what are the four common implementations for analysing solids ?

Answer 6

MALDI

SIMS
LAESI

DESI