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Manufacturing > Manufacturing of Capsules > Flashcards

Manufacturing of Capsules Flashcards

1
Q

Hard Gelatin Capsule

A

Telescoping Capsule / Dry-filled Capsule

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2
Q

Gelatin shells are manufactured in separate process by ____________ or ____________ of the desired shape and diameter into a* temperature-controlled reservoir* of melted gelatin mixture

A

Gelatin shells are manufactured in separate process by dipping pins or pegs (manganese bronze) of the desired shape and diameter into a temperature-controlled reservoir of melted gelatin mixture

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3
Q

Two step process in Manufacturing of Capsule

A
  1. Shell Manufacturing
  2. Filling
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4
Q

Steps in making Empty Gelatin Capsules

A
  1. Dipping
  2. Spinning/Rotation
  3. Drying
  4. Stripping
  5. Trimming
  6. Joining
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5
Q

Pairs of stainless steel pins are dipped into the dipping solution to simultaneously from the cap and body

A

Dipping

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6
Q

The pins are rotated to distribute the gelatin over the pins uniformly and to avoid formation of beads at capsule ends.

A

Spinning/Rotating

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7
Q

The gelatin is dried by blast of cool air to form a hard shell

A

Drying

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8
Q

Series of bronze jaws strips the cap and body portions of the capsules from the pins

A

Trimming

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9
Q

The stripped cap and body portions are trimmed to the required length

A

Trimming

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10
Q

The cap and body portion are joined and ejected from the machine

A

Joining

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11
Q

Filling of Hard Gelatin Capsules

A

Rectification
Separation
Filling
Replacement of caps and ejection of filled capsules

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12
Q

The empty capsules are oriented on the same direction

A

Rectification

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13
Q

Separation of cap and body

A

Rectification

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14
Q

Dosing of fill material

A

Filling

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15
Q

The cap and body bushing portion are rejoined and ejected

A

Replacemnt of caps
Ejection of filled capsule

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16
Q

Special Technique: Sealing

A

Gelatin Banding – seals with a band of gelatin
Heat Welding – fuses cap to body through double wall thickness
Thermal Coupling – uses liquid wetting agent to lower melting point between cap and body then bonds

17
Q

Consist of a liquid or semisolid matrix inside a one-piece outer gelatin shell

A

Soft Gelatin Capsule

18
Q

Methods used in Soft Gelatin Capsules

A

Plate Process
Rotary Die Process
Reciprocating Die Process

19
Q

Oldest method & uses set of molds to form the capsules

A

Plate Process

20
Q

Liquid gelatin flowing from tank is formed into two continuous gelatin ribbon by the machine and brought together between twin rotating die

A

Rotary Die Process

Manufacturing (13 decks)

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