management Of Patients With Oncologic Disorders Ch 12 Management of patients with oncologic disorders Flashcards

1
Q

Alopecia 

A

Hair loss

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2
Q

Anaplasia

A

Pattern of growth in which cells lack normal characteristics and differ in shape and organization, with respect to their cells of origin; usually, anaplastic cells are malignant

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3
Q

Angiogenesis

A

Growth of new blood vessels that allow cancer cells to grow

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4
Q

Apoptosis

A

A normal cell mechanism of programmed cell death

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5
Q

Benign

A

Not cancerous; benign tumors may grow, but are unable to spread to other organs or body body

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6
Q

Brachytherapy

A

Delivery of radiation therapy through internal implants, placed inside or adjacent to the tumor

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7
Q

Cancer

A

A group of disorders, characterized by abnormal cell, perforation, in which cells ignore growth-regulating signals in the surrounding environment

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8
Q

Carcinogenesis

A

Process of transforming normal cells into malignant cells

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9
Q

Chemotherapy

A

The use of medication’s to kill tumor cells by interfering with cellular functions and reproduction

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10
Q

Cytokines

A

Messenger substances that may be released by a cell to create an action at that site or may be carried by the bloodstream to a distant site before being activated (Synonyms, bio, chemical, mediators, inflammatory mediations )

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11
Q

Extravasaton

A

A leakage of intravenous medication from the veins into the subcutaneous tissue

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12
Q

Grading

A

Identification of the type of tissue from which the tumor originated and the degree to which the tumor cells retain the functional and structural characteristics of the tissue of origin

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13
Q

Graft versus host disease, GVHD

A

An immune response initiated by T lymphocytes of donor tissue against the recipients tissues (Skin, gastrointestinal, tract, liver ) An undesirable response 

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14
Q

Graft versus tumor effect 

A

The donor immune cell response against the malignancy; a desirable response

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15
Q

Immunotherapy

A

Do use of medication or other agents to stimulate or suppress components of the immune system to kill cancer cells

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16
Q

Malignant

A

Having cells are processes that are characteristic of cancer

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17
Q

Metastasis 

A

Spread of cancer cells from the primary tumor to distant sites

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18
Q

Mucositis

A

Inflammation of the lining of the mouth, throat, and gastrointestinal tract often associated with cancer therapies

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19
Q

Myelosuppression

A

Suppression of the blood cell producing function of the bone marrow

20
Q

Nadir

A

The lowest serum level of blood cells (White blood cells, red blood cells, and platelets ) After therapy that has toxic effects on the bone marrow. Clinically, the Nadir is most often used to describe the lowest absolute neutrophil count following chemotherapy. 

21
Q

Neoplasia

A

Uncontrolled cell growth and follows no physiologic demand; cancer

22
Q

Neutropenia

A

Abnormally, low, absolute neutrophil count

23
Q

Oncology

A

Field or study of cancer

24
Q

Palliation

A

Relief of symptoms and promotion of comfort and quality of life, regardless of the disease stage

25
Precision medicine
Using advances in research, technology and policies to develop individualized plans of care to prevent and treat disease
26
Radiation therapy
The use of ionizing radiation to kill malignant cells
27
Staging
Process of determining the extent of disease, including tumor, size, and spread, or metastasis to distant sites
28
Stomatitis 
Inflammation of the oral tissues, often associated with some chemotherapeutic agents and radiation therapy to the head and neck region
29
Targeted Therapies
The use of medication or other agents to kill or prevent the spread of cancer cells by targeting specific part of the cell, with less negative effects on healthy cells
30
Thrombocytopenia
Decrease in the number of circulating platelets; associated with the potential for bleeding
31
Toxicity
An unfavorable and unintended sign, symptoms, or condition associated with cancer treatment
32
Neoplasia
Uncontrolled growth that follows no physiologic demand
33
Carcinoma
Epithelial squamous cell
34
Sarcoma
Connective tissue bone bone
35
Myeloma
Plasma cells
36
Lymphoma
Lymphocytes
37
Leukemia
Cells in the bone marrow
38
Anti tumor antibiotics
Adriamycin: cardiotoxic
39
Alkylating agents
Cisplatin leda to renal failure; causes red/orange pee
40
Anti metabolite
Methotrexate
41
Nonspecific immuno therapy
Boost immune system Cytokines help with destruction of tumor , Inhibiting growth factors
42
Mono colonial antibodies MoABs
Destroys cancer cell and spares, healthy cells Antibodies are created and therapeutically used 
43
Cachexia
Increased, metabolic demand, impaired metabolism or glucose and lipids continued, weight loss
44
Superior vena cava syndrome, SVC
Sudden, impaired venous drainage
45
Spinal cord compression
Motor and sensory changes
46
Hypercalcemia
Fatigue, weakness, confusion, arrhythmias, decreased, LOC
47
Tumor lysis syndrome
Cramps, paresthesia, increased blood pressure, flank pain Life-threatening Large, bulky tumor is being destroyed, intracellular contents are spelled. Uric acid, potassium phosphorus can lead to ARF acute renal failure