Management of Labour Flashcards

1
Q

A primigravida presents in term labour, 39/40, at 4cm, planning vaginal breech delivery. Contraction frequency is regular and there are no CTG concerns. Some 4 hours later you are called to review the CTG. There is a baseline rate of 145 bpm with reduced variability for the last 60 minutes and repetitive decelerations, some of which appear late. You perform a vaginal examination and find the cervix 6cm, buttocks presenting at -1 above ischial spines. What management do you recommend?

a. Delivery by caesarean section Cat. 1
b. Delivery by caesarean section Cat. 2
c. FBS
d. Oxytocin augmentation
e. Give fluids, change position and review the CTG in 30 minutes

A

B - Delivery by caesarean section Cat. 2

This scenario describes acceptable labour progress though in the context of a pathological CTG (>50 minutes reduced variability, late decelerations). While in a cephalic labour, a trial of conservative measures or FBS to further assess the fetal condition may be performed, neither are appropriate with a breech baby (though FBS of the buttocks is technically possible, it is not recommended). While judicious use of oxytocin for purposes of augmentation may be considered in breech labours, it is neither indicated here nor appropriate with such a CTG. The guideline states that ‘where EFM is considered abnormal before the active second stage, caesarean delivery is recommended’ – a category 2 would be appropriate in this scenario.

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2
Q

A Para 3 presents in labour un-booked, with no history of antenatal care in this pregnancy. She has had 3 previous vaginal deliveries and on examination appears to be in established labour at 5cm though membranes are intact. SFH is recorded as 38cm. You note the presence of herpetic lesions on the external genitalia which the patient informs you appeared 7 days ago and she has no recollection of having had genital herpes in the past. What management do you suggest?

a. Delivery by Cat. 1 LSCS
b. Delivery by Cat. 2 LSCS
c. As labour established and multiparous, vaginal delivery under IV acyclovir cover
d. Providing expected progress is made on subsequent examination, vaginal delivery with acyclovir for the neonate at birth
e. Providing expected progress is made on subsequent examination, vaginal delivery with IV acyclovir for both patient and neonate at birth

A

B - Delivery by Cat. 2 LSCS

This history is suggestive of primary genital HSV infection and delivery by caesarean section is the preferred mode of delivery here. There is still some benefit to be gained despite active labour already having started, particularly as membranes are intact. There is no immediate threat to the life of the mother nor her fetus therefore a Cat. 2 caesarean would be most appropriate.

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3
Q

A patient with a history of primary genital herpes in the third trimester is quite adamant after counselling, that she wishes to proceed with vaginal birth. What intrapartum regimen of acyclovir so you advise during labour?

a. 400mg 8 hourly orally
b. 400mg 8 hourly IV
c. 800mg 5x/day orally
d. 5mg/kg 8 hourly IV
e. 20mg/kg 8 hourly IV

A

D - 5mg/kg IV 8-hourly

5mg/kg IV 8-hourly is the recommended dose of acyclovir for patients with a primary episode in the third trimester or last 6 weeks who wish to proceed with vaginal delivery. Equivalent to 300mg in a 60kg patient.

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4
Q

A primigravida presents with membrane rupture at 37+4/40 though does not appear to be in active labour. You note the results of a HVS performed earlier in the pregnancy which demonstrated GBS carriage. What is the most appropriate management in this case?

a. Administer erythromycin 250mg QDS and offer IOL in 24 hours if not in spontaneous labour
b. IOL in 24 hours if no spontaneous labour
c. Commence IV Benzylpenicillin at the usual dose and offer IOL in 4-6 hours if no contractions in the meantime
d. Commence IV Benzylpenicillin at the usual dose and offer immediate IOL
e. Advise delivery by Cat 2 LSCS

A

D - Commence IV Benzylpenicillin and offer immediate induction of labour

Routine management here in the absence of GBS would be to offer induction of labour in 24 hours if the woman does not labour spontaneously – in the context of known GBS carriage (or another indication for IAP), it is prudent to expedite this and proceed with IOL immediately.

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5
Q

What is the dose of Benzylpenicillin for intrapartum antibiotic prophylaxis in GBS?

a. 4 gram stat and 1 gram 4 hourly IV
b. 1.5 grams 4 hourly IV
c. 3 grams stat and 1 gram 6 hourly IV
d. 3 grams state and 1.5 grams 4 hourly IV
e. 1.5 grams stat and 1 gram 4 hourly IV

A

D - 3 grams state and 1.5 grams 4 hourly IV

The recommended antibiotic course for GBS prophylaxis is labour is 3 grams of Benzylpenicillin as a loading dose, then 1.5grams every 4 hours until delivery thereafter.

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6
Q

A primigravida, known to be GBS positive after opportunistic testing earlier in pregnancy arrives on delivery suite at 38/40 in spontaneous labour. You note from her hand-held maternity record that she has an allergy to penicillin. On discussing this further with the patient she discloses that on a few occasions after taking amoxicillin for urinary infections, she has developed an itch. Which antibiotic protocol do you suggest?

a. Benzylpenicillin – 3 grams loading and 1.5 grams 4 hourly
b. Cefuroxime 1.5 grams 8 hourly
c. Vancomycin 1 gram 12 hourly
d. Gentamicin 300mg 24 hourly
e. Erythromycin 250mg QDS

A

B - Cefuroxime 1.5 grams 8 hourly

Antibiotic choice for GBS prophylaxis in the context of penicillin allergy depends on the nature/severity of the allergy. If on questioning the reaction described is unlikely to represent a true allergy – i.e. vomiting – then the penicillin should be given. If suggestive of an allergy to beta-lactams, but one that is not severe
(i.e. no anaphylaxis, angioedema, respiratory distress or urticaria), then a cephalosporin can be administered intravenously (e.g. cefuroxime, 1.5 g loading dose followed by 750 mg every 8 hours). If the allergy to beta-lactams is
severe then intravenous vancomycin (1 g every 12 hours) is recommended.

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7
Q

A Para 3, known to be GBS positive after opportunistic testing earlier in pregnancy arrives on delivery suite at 38/40 in spontaneous labour. You note from her hand-held maternity record that she has an allergy to penicillin. On discussing this further with the patient she discloses that the last time she had a UTI, she vomited after taking amoxicillin though thinks she had taken it in the past without a problem. Which antibiotic protocol do you suggest?

a. Benzylpenicillin – 3 grams loading and 1.5 grams 4 hourly
b. Cefuroxime 1.5 grams 8 hourly
c. Vancomycin 1 gram 12 hourly
d. Gentamicin 300mg 24 hourly
e. Erythromycin 250mg QDS

A

A - Benzylpenicillin 3 grams loading and 1.5 grams 4 hourly

Antibiotic choice for GBS prophylaxis in the context of penicillin allergy depends on the nature/severity of the allergy. If on questioning the reaction described is unlikely to represent a true allergy – i.e. vomiting – then the penicillin should be given. If suggestive of an allergy to beta-lactams, but one that is not severe
(i.e. no anaphylaxis, angioedema, respiratory distress or urticaria), then a cephalosporin can be administered intravenously (e.g. cefuroxime, 1.5 g loading dose followed by 750 mg every 8 hours). If the allergy to beta-lactams is
severe then intravenous vancomycin (1 g every 12 hours) is recommended.

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8
Q

A Para 1 attends delivery suite in preterm labour at 34+3/40 with ruptured membranes. On review, you note that a swab taken at 12/40 during an admission with threatened miscarriage was negative for infection or significant culture. The patient’s handheld maternity record also discloses a history of severe penicillin allergy in infancy with anaphylactic shock. What antibiotic prophylaxis, if any, do you advise in labour?

a. No prophylaxis necessary
b. Cefuroxime 1.5 grams 8 hourly
c. Vancomycin 1 gram 12 hourly
d. Gentamicin 300mg 24 hourly
e. Erythromycin 250mg QDS

A

C - Vancomycin 1 gram 12 hourly

Antibiotic choice for GBS prophylaxis in the context of penicillin allergy depends on the nature/severity of the allergy. If on questioning the reaction described is unlikely to represent a true allergy – i.e. vomiting – then the penicillin should be given. If suggestive of an allergy to beta-lactams, but one that is not severe
(i.e. no anaphylaxis, angioedema, respiratory distress or urticaria), then a cephalosporin can be administered intravenously (e.g. cefuroxime, 1.5 g loading dose followed by 750 mg every 8 hours). If the allergy to beta-lactams is
severe then intravenous vancomycin (1 g every 12 hours) is recommended.

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9
Q

A patient attends the delivery suite in early labour, though is struggling with pain and requests an epidural. Owing to her VTE risk assessment score of 3, she has been on antenatal LMWH thromboprophylaxis which she last took at 6 o’clock last night. It is now 9am. How long after a dose of prophylactic LMWH can regional anaesthetic safely be sited?

a. 4 hours
b. 6 hours
c. 12 hours
d. 18 hours
e. 24 hours

A

C - 12 hours

Regional analgesia should – wherever possible – be avoided until at least 12 hours from the last prophylactic dose of LMWH. For this reason (amongst others), women are often advised to omit a dose if they believe labour to be starting. Alternatives such as an opiate based PCA may be offered to those in whom LMWH dosing precludes epidural analgesia.

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10
Q

A patient attends the delivery suite in early labour, though is struggling with pain and requests an epidural. After developing a DVT at 32/40, she has been on treatment dose LMWH which she last took at 6 o’clock last night. It is now 9am. How long after a treatment dose of LMWH can regional anaesthetic safely be sited?

a. 6 hours
b. 12 hours
c. 24 hours
d. 36 hours
e. 48 hours

A

C - 24 hours

Following a treatment dose of LMWH, regional analgesia should be avoided where possible for 24 hours. It may be reasonable in certain circumstances to offer induction of labour to patients on treatment (or high-prophylactic) dose LMWH in order to facilitate pain relief options around delivery.

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11
Q

A midwife is attending a women in early labour at home. Auscultation of the fetal heart immediately after SROM reveals a prolonged bradycardia with the FHR at 90bpm. A vaginal examination in performed and the umbilical cord found to be prolapsed beyond the fetal head through an incompletely dilated cervix (6cm). Urgent hospital transfer is arranged. Which of the following conservative methods should NOT be used in this patient?

a. Bladder filling with 750ml sterile water
b. Maternal left lateral position
c. Terbutaline 0.25 micrograms s/c
d. Manual replacement of the cord
e. Manual displacement of the fetal head

A

D - Manual replacement of the cord

When cord prolapse is diagnosed, the priority for immediate management should be seek assistance and plan immediate delivery in theatre. While in the inpatient setting, manual elevation of the presenting part may be all that is required while awaiting transfer, the midwife encountering cord prolapse at a homebirth may need to give consideration to additional measures – filling the bladder with 500-750ml of sterile water to elevate the fetal head, administration of tocolytic terbutaline and adoption of the knee-chest or left lateral position (with a pillow under the left hip) are all described and may be of benefit. One method which should not be employed however is attempting manual replacement of the cord to permit continuation of labour. Handling loops of cord outwith the vagina can induce vasospasm, further restricting fetal blood flow.

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12
Q

What is the effect on the average time of labour with the additional of 200mg mifepristone to a misoprostol regimen for intra-uterine fetal death?

a. No change
b. Reduces by 2 hours
c. Reduces by 4 hours
d. Reduces by 7 hours
e. Reduces by 9 hours

A

D - Reduces by 7 hours

There is evidence to suggest that the addition of mifepristone to misoprostol induction of labour regimens may shorten the time interval between induction and delivery by approximately 7 hours though there is no other apparent benefit with its use. A single dose of mifepristone 200mg is appropriate for this indication.

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13
Q

What is the recommended induction regimen for women with IUFD beyond 27/40?

a. Misoprostol 25mg 8 hourly
b. Misoprostol 400mcg 8 hourly
c. Misoprostol 50mcg 4 hourly
d. Misoprostol 200mcg 3 hourly
e. Misoprostol 100mcg 6 hourly

A

C - Misoprostol 50mcg 4 hourly

The use of misoprostol in pregnancy in the UK is off-label though its role for IOL in IUFD is endorsed by NICE. Vaginal administration is as effective as oral though with a lower incidence of adverse side-effects. The suggested doses are as follows:

  • Up to and including 26+6/40: 100 micrograms 6 hourly
  • From 27+0/40 onwards: 50mcg 4 hourly

Both regimens are suggested for up to 24 hours, as required.

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14
Q

What is the recommended induction regimen for women with IUFD <26+6?

a. Misoprostol 25mg 6 hourly
b. Misoprostol 400mcg 8 hourly
c. Misoprostol 50mcg 4 hourly
d. Misoprostol 200mcg 3 hourly
e. Misoprostol 100mcg 6 hourly

A

E - Misoprostol 100mcg 6 hourly

The use of misoprostol in pregnancy in the UK is off-label though its role for IOL in IUFD is endorsed by NICE. Vaginal administration is as effective as oral though with a lower incidence of adverse side-effects. The suggested doses are as follows:

  • Up to and including 26+6/40: 100 micrograms 6 hourly
  • From 27+0/40 onwards: 50mcg 4 hourly

Both regimens are suggested for up to 24 hours, as required.

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15
Q

Titrated oxytocin is now the commonest adjunct used for induction of labour and maintaining uterine contractions. What is the mechanism of action of oxytocin?

a. Increases prostaglandin release from the chorioamniotic membrane
b. Increases release of interleukin 6 and 8 from the amniochoriodecidual space
c. Binding to oxytocin receptors in the uterus resulting in myometrial contractility
d. Acting directly on the cervix causing it to soften and dilate
e. Acting on receptors on the nipples uterus and cervix to cause contractions, cervical dilatation and effacement

A

C - Binding to oxytocin receptors in the uterus resulting in myometrial contractility

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16
Q

What is the most common reason for transfer from midwifery-led to obstetric-led care in labour?

a. Concern regarding fetal heart rate
b. Meconium passage
c. Failure to progress
d. Perineal trauma
e. Request for regional analgesia

A

C - Failure to progress

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17
Q

A low risk primigravida presents in early labour for assessment. What should be the nature of fetal monitoring undertaken as part of this assessment?

a. Computerised CTG until criteria met
b. Non-computerised CTG for 20 minutes
c. Auscultation of fetal heart for 30 seconds immediately after a contraction
d. Auscultation of fetal heart for 60 seconds immediately after a contraction
e. Auscultation of fetal heart during and for 30 seconds after a contraction

A

D - Auscultation of the fetal heart for 60 seconds immediately after a contraction

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18
Q

A patient booked for midwifery led care is assessed in her local birthing unit. On arrival her blood pressure is noted to be elevated at 155/95mmHg. Urine dipstick testing is negative for protein. What action should be taken here?

a. Commence 5-minute interval BP checks
b. Repeat BP in 30 minutes
c. Repeat BP in 60 minutes
d. Arrange immediate transfer to obstetric led car
e. Administer anti-hypertensives and arrange transfer to obstetric led care

A

B - Repeat BP in 30 minutes

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19
Q

A 41 year old primigravida (IVF pregnancy) with a booking BMI of 35, is assessed upon arrival at her local midwifery-led birthing unit in labour at 37+5/40. The fetus is cephalic, 5/5 palpable per abdomen and the fetal heart rate on auscultation is 115/min. Results of a recent full blood count are reviewed on which Hb is noted to be 90g/L. What aspect of this history should prompt transfer to obstetric led intrapartum care?

a. Maternal age
b. IVF pregnancy
c. BMI
d. Fetal engagement
e. Hb

A

D - Fetal engagement

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20
Q

What is the maximum water temperature advised for women who request immersion in water during labour?

a. 30C
b. 37.5C
c. 40C
d. 45C
e. 50C

A

B - 37.5C

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21
Q

How often should water temperature be checked where a patient is labouring in water?

a. Every 10 minutes
b. Every 15 minutes
c. Every 30 minutes
d. Every hour
e. When water is initially drawn, no need to check thereafter if within recommended range

A

D - Every hour

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22
Q

A patient receives 100mg of pethidine during the first stage of labour. Shortly afterwards she requests immersion in water. How long after receiving opioid analgesia should patients wait prior to entering water during labour?

a. 15 minutes
b. 30 minutes
c. 1 hour
d. 2 hours
e. No restrictions

A

D - 2 hours

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23
Q

How long after insertion of epidural analgesia should anaesthetic opinion be sought if patients are not pain free?

a. 5 minutes
b. 10 minutes
c. 15 minutes
d. 30 minutes
e. 45 minutes

A

D - 30 minutes

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24
Q

How often should the level of sensory block be checked during labour in women with regional analgesia?

a. Every 15 minutes
b. Every 30 minutes
c. Every hour
d. Every 2 hours
e. Every 3 hours

A

C - Every hour

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25
Q

What frequency of intermittent auscultation is advised in low risk women during the first stage of labour?

a. 60 seconds after every contraction
b. 60 seconds after a contraction every 10 minutes
c. 30 seconds after every contraction
d. 30 seconds after a contraction every 10 minutes
e. 30 seconds after a contraction every 15 minutes

A

B - 60 seconds after a contraction every 10 minutes

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26
Q

After which time period on intrapartum CTG does decreased variability become a non-reassuring feature?

a. 20 minutes
b. 30 minutes
c. 40 minutes
d. 50 minutes
e. 60 minutes

A

B - 30 minutes

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27
Q

After which time period on intrapartum CTG does decreased variability become an abnormal feature?

a. 40 minutes
b. 50 minutes
c. 60 minutes
d. 90 minutes
e. 120 minutes

A

B - 50 minutes

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28
Q

After which time period on intrapartum CTG does increased variability (>25/min) variability become a non-reassuring feature?

a. 15 minutes
b. 30 minutes
c. 45 minutes
d. 60 minutes
e. 90 minutes

A

A - 15 minutes

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29
Q

After which time period on intrapartum CTG does increased variability become an abnormal feature?

a. 25 minutes
b. 50 minutes
c. 75 minutes
d. 90 minutes
e. 120 minutes

A

A - 25 minutes

30
Q

Which of the following is NOT a ‘concerning’ feature of variable decelerations on an intrapartum CTG?

a. Lasting more than 60 seconds
b. W-shaped
c. Lack of variability within deceleration
d. Failure to return to baseline
e. Nadir of deceleration occurring prior to peak of contraction

A

E - Nadir of deceleration occurring prior to peak of contraction

31
Q

After which time period on intrapartum CTG do late decelerations become an abnormal feature?

a. 20 minutes
b. 30 minutes
c. 40 minutes
d. 50 minutes
e. Late decelerations are always an abnormal feature

A

B - 30 minutes

32
Q

After which time period on intrapartum CTG do repetitive variable decelerations with concerning features become an abnormal feature?

a. 20 minutes
b. 30 minutes
c. 40 minutes
d. 50 minutes
e. 60 minutes

A

B - 30 minutes

33
Q

What is the usual cause of variable decelerations on an intrapartum CTG?

a. Fetal head compression
b. Umbilical cord compression
c. Fetal acidosis
d. Fetal hypoxia
e. Maternal hypotension

A

B - Umbilical cord compression

34
Q

What is a normal fetal lactate on an FBS taken during labour?

a. <2.5
b. <3.1
c. <3.8
d. <4.1
e. <4.8

A

D - <4.1

35
Q

Above what level is fetal lactate on an FBS sample considered abnormal?

a. >3.8
b. >4.1
c. >4.8
d. >5.1
e. >5.5

A

C - >4.8

36
Q

An FBS is taken during labour on a patient with a pathological CTG and a pH result of 7.23 obtained. Assuming the CTG remains pathological, when should this – if at all - be repeated?

a. No indication to repeat
b. 30 minutes
c. 45 minutes
d. 60 minutes
e. 90 minutes

A

B - 30 minutes

37
Q

How long after delivery should CTG traces be retained as part of the medical record (assuming the infant is well at birth and there are no concerns regarding possible developmental delay)?

a. 5 years
b. 15 years
c. 25 years
d. 30 years
e. 50 years

A

C - 25 years

38
Q

What proportion of women who experience pre-labour rupture of membranes at term, can be expected to labour within 24 hours of the event?

a. 1/4 (25%)
b. 1/3 (33%)
c. 1/2 (50%)
d. 3/5 (60%)
e. 4/5 (80%)

A

D - 3/5 (60%)

39
Q

How often should contraction frequency be documented on the partogram in labour?

a. 10 minutes
b. 15 minutes
c. 30 minutes
d. Hourly
e. 2 hourly

A

C - 30 minutes

40
Q

How often should blood pressure be checked in otherwise well women in established labour?

a. 15 minutes
b. 30 minutes
c. Hourly
d. 2 hourly
e. 4 hourly

A

D - 2 hourly

41
Q

How long following an amniotomy performed for suspected failure to progress in the first stage should a VE be undertaken to assess progress?

a. 1 hour
b. 2 hours
c. 3 hours
d. 4 hours
e. Only if indicated

A

B - 2 hours

42
Q

What frequency of intermittent auscultation should be undertaken in the second stage of labour?

a. After every contraction for 60s
b. Once every 5 minutes, after a contraction, for 60s
c. Once every 10 minutes, after a contraction, for 60s
d. Once every 15 minutes, after a contraction, for 60s
e. Once every 20 minutes, after a contraction, for 60s

A

B - Once every 5 minutes, after a contraction, for 60s

43
Q

Within how many hours of the start of the active second stage should birth be expected to occur in primigravidae and multigravidae respectively?

Primigravida Multigravida

a. 2 hours 1 hour
b. 2 hours 2 hours
c. 3 hours 1 hour
d. 3 hours 2 hours
e. 4 hours 3 hours

A

D - 3 hours in primigravida; 2 hours in multigravidae

44
Q

What reduction in post-partum haemorrhage greater than 1 litre is achieved by routine use of oxytocic drugs for the third stage of labour compared with a ‘physiological’ third stage?

a. 25%
b. 30%
c. 50%
d. 60%
e. 75%

A

D - 60%

45
Q

What is the principle side effect of routine use of uterotonic drugs for the third stage of labour?

a. Abdominal pain
b. Delay in passing urine
c. Constipation
d. Gastro-oesophageal reflux
e. Nausea and vomiting

A

E - Nausea and vomitting

46
Q

How long after an active and physiological third stage respectively should diagnose of delay be made?

Physiological Active

a. 90 minutes 60 minutes
b. 60 minutes 60 minutes
c. 60 minutes 30 minutes
d. 45 minutes 30 minutes
e. 30 minutes 30 minutes

A

C - 60 minutes physiological; 30 minutes active

47
Q

Worldwide, what proportion of infants are born preterm?

a. 1 in 75
b. 1 in 50
c. 1 in 25
d. 1 in 15
e. 1 in 10

A

E - 1 in 10

48
Q

What is the most common pattern of paralysis seen in infants with cerebral palsy secondary to prematurity?

a. Hemiplegia
b. Diplegia
c. Quadriplegia
d. Upper limb spasticity
e. Ataxia

A

B - Diplegia

49
Q

Until what gestation should MgSO4 be offered routinly for fetal neuroprotection according to NICE/RCOG guidance?

a. 28/40
b. 29/40
c. 30/40
d. 32/40
e. 34/40

A

C - 30/40

It may be considered up until 33+6 in certain circumstances

50
Q

In planned preterm birth, what is the ideal timing of magnesium sulphate administration prior to the birth?

a. 24 hours
b. 12 hours
c. 6 hours
d. 4 hours
e. 2 hours

A

D - 4 hours

51
Q

What is the maximum duration of treatment with magnesium sulphate for fetal neuroprotection in preterm birth?

a. Loading dose only
b. 6 hours
c. 12 hours
d. 24 hours
e. 48 hours

A

D - 24 hours

52
Q

Overall in the UK, what percentage of infants deliver preterm?

a. 0.5%
b. 2%
c. 7%
d. 11%
e. 15%

A

C - 7%

7.3% of infants in the UK deliver preterm on average.

53
Q

What proportion of premature birth is iatrogenic – intentionally delivered preterm in either maternal or fetal interest?

a. 10%
b. 25%
c. 40%
d. 50%
e. 75%

A

B - 25%

A quarter of all preterm birth is a result of decision making by obstetricians in the maternal or fetal interest

54
Q

Which of the following women should be offered prophylactic cervical cerclage?

a. 29 year primigravida who attends for a fetal anomaly scan at 19 weeks of gestation. The sonographer notes the cervix appears short and is found to be 19mm on TVUSS. She is asymptomatic and the scan is otherwise normal.
b. A Para 2 has had 2 preterm vaginal deliveries at 25 and 29 weeks. Her cervical length on scan is 26mm
c. A Para 1 who’s first pregnancy resulted in a caesarean delivery at 29 weeks of gestation after she experienced an eclamptic fit. Her cervical length has been measured at 23mm on scan.
d. A Para 1 who had an IUD at 31 weeks of gestation and laboured spontaneously has a cervical length of 24mm on scan today
e. A Para 0 with a history of 2 pregnancies losses, both of which occurred at 15/40. Cervical length is 20mm.

A

D - A Para 1 who had an IUD at 31 weeks of gestation and laboured spontaneously has a cervical length of 24mm on scan today

This question is a recurring theme - knowing the criteria for insertion of cerclage is very much worthwhile:

OFFER cerclage (or progesterone) to women who have BOTH:

• A history of spontaneous preterm birth or 2nd trimester loss between 16+0 and 34+0/40

AND

• Evidence of a short cervix (<25mm) on TV USS between 16+0 and 24+0

CONSIDER cerclage in women who have evidence of a short cervix (<25mm) on TV USS between 16+0 and 24+0 and EITHER:

  • Previous PPROM
  • History of ‘cervical trauma’
55
Q

A 24 year old is referred for cervical length scans in her second pregnancy after experiencing a miscarriage with PROM and painless cervical dilatation at 21 weeks of gestation in her first. She attends for the first such scan at 18 weeks of gestation and the cervical length is noted to be 20mm with no evidence of funnelling. What management is most appropriate here?

a. Vaginal progesterone
b. Cervical cerclage
c. Vaginal progesterone and cervical cerclage
d. Vaginal progesterone or cervical cerclage depending on patient’s preference
e. No treatment indicated

A

D - Vaginal progesterone or cervical cerclage depending on patient’s preference

Either progesterone or cerclage may be offered to patients who meet the criteria stated in the NICE guidelines

56
Q

A 25 year old attends for her mid-trimester scan and cervical length is noted to be 21mm with no evidence of funnelling. What management is most appropriate here?

a. Vaginal progesterone
b. Cervical cerclage
c. Vaginal progesterone and cervical cerclage
d. Vaginal progesterone or cervical cerclage depending on patient’s preference
e. No treatment indicated

A

A - Vaginal progesterone

Vaginal progesterone may be offered to women with an incidental finding of a short cervix on scan in the absence of a history which would suggest cerclage were needed

57
Q

A patient is admitted with confirmed pre-labour preterm rupture of membranes at 34 weeks in her first pregnancy. You explain that a course of antibiotic therapy is interested - what do you prescribe first line?

a. Amoxicillin 250mg TDS for 7 days
b. Clarithromycin 500mg TDS for 7 days
c. Metronidazole 400mg TDS for 8 days
d. Cefradine 250mg BD for 5 days
e. Erythromycin 250mg TDS for 10 days

A

E - Erythromycin 250mg TDS for 10 days

58
Q

A patient admitted with preterm, pre-labour rupture of membranes at 32 weeks gestation discloses an allergy to erythromycin. What antibiotic should be used second line assuming there are no contraindications?

a. Penicillin
b. Cefradine
c. Vancomycin
d. Co-amoxiclav
e. Clarithromycin

A

A - Penicillin

Where erythromycin is contraindicated or not tolerated, oral penicillins may be used instead. Co-amoxiclav specifically however should NOT be used.

59
Q

Until what gestation should rescue cerclage be considered to patients with preterm cervical dilatation?

a. 23+6
b. 25+6
c. 27+6
d. 31+6
e. 33+6

A

C - 27+6

Rescue cerclage may be offered to women between 16+0 and 27+6 weeks with a dilated cervix and exposed, though unruptured, membranes. Do not offer rescue cerclage to women with signs of infection, active vaginal bleeding or uterine contraction.

60
Q

From what gestation should rescue cerclage be offered to patients with a suitable history?

a. 16/40
b. 18/30
c. 22/40
d. 23/40
e. 24/40

A

A - 16/40

Rescue cerclage may be offered to women between 16+0 and 27+6 weeks with a dilated cervix and exposed, though unruptured, membranes. Do not offer rescue cerclage to women with signs of infection, active vaginal bleeding or uterine contraction.

61
Q

A primigravida presents with threatened preterm labour at 31 weeks of gestation. You decide to prescribe a course of steroids and tocolysis. What tocolytic agent should be used first line?

a. GTN
b. Atosiban
c. Terbutaline
d. Nifedipine
e. Salbutamol

A

D - Nifedipine

Nifedipine is first line and oxytocin receptor antagonists (atosiban) second if contraindicated. Beta-mimetics should NOT be used.

62
Q

Until what gestation should corticosteroids be routinely prescribed to women with threatened pre-term labour by NICE guidelines?

a. 30+6
b. 31+6
c. 33+6
d. 34+6
e. 35+6

A

C - 33+6/40

NICE guidelines suggest the following thresholds regarding the use of steroids for fetal lung maturity in premature infants:

  • Between 23+0 and 23+6/40:
    • Discuss with the mother and family the use of steroids in the context of her specific circumstances
  • Between 24+0 and 25+6/40:
    • Consider steroids
  • Between 26+0 and 33+6/40:
    • Offer steroids
  • Between 34+0 and 35+6/40:
    • Consider steroids
63
Q

Until what gestation should magnesium sulphate be routinely prescribed to women with threatened pre-term labour?

a. 28+6
b. 29+6
c. 30+6
d. 31+6
e. 32+6

A

B - 29+6

Regarding magnesium sulphate, NICE suggest the following:

Between 24+0 and 29+6/40
• Offer

Between 30+0 and 33+6/40
• Consider

64
Q

Until what gestation should magnesium sulphate be considered in women with threatened preterm labour?

a. 29+6
b. 30+6
c. 31+6
d. 33+6
e. 34+6

A

D - 33+6

Regarding magnesium sulphate, NICE suggest the following:

Between 24+0 and 29+6/40
• Offer

Between 30+0 and 33+6/40
• Consider

65
Q

A primigravida is admitted at 26 weeks of gestation with threatened preterm labour. Your consultant has requested that you prescribe magnesium sulphate for fetal neuroprotection. What is the recommended dose of magnesium sulphate for fetal neuroprotection?

a. 1 gram bolus loading, 0.5g per hour for 24 hours
b. 1.5 gram bolus loading, 0.25g per hour for 24 hours
c. 3 gram bolus loading, 1g per hour for 24 hours
d. 4 gram bolus loading, 1g per hour for 24 hours
e. 1 gram per hour for 24 hours

A

D - 4 gram bolus loading, 1g per hour for 24 hours

66
Q

How often should women on magnesium sulphate be checked for signs of magnesium toxicity where this is used for fetal neuroprotection?

a. Every 15 minutes
b. Every 30 minutes
c. Every hour
d. Every 2 hours
e. Every 4 hours

A

E - Every 4 hours

67
Q

What is the earliest gestation at which use of a fetal scalp electrode may be considered?

a. 30/40
b. 32/40
c. 34/40
d. 36/40
e. 37/40

A

C - 34/40

FSE, FBS and ventouse should all be used only from 34/40 onwards

68
Q

A primigravida is admitted with threatened pre-term labour at 33 weeks of gestation. At 8cm there is some concern on the CTG and you considered what next steps may be appropriate. What is the earliest gestation at which use of fetal blood sampling may be considered?

a. 30/40
b. 32/40
c. 34/40
d. 36/40
e. 37/40

A

C - 34/40

FSE, FBS and ventouse should all be used only from 34/40 onwards

69
Q

A woman admitted in preterm labour enquires about delayed cord clamping after the birth. What duration of delayed cord clamping is advised in preterm infants where appropriate?

a. At least 30 seconds, no longer than 3 minutes
b. At least 30 seconds, no longer than 2 minutes
c. At least 60 seconds, no longer than 2 minutes
d. At least 2 minutes, no longer than 3 minutes
e. At least 2 minutes, no longer than 4 minutes

A

A - At least 30 seconds, no longer than 3 minutes

70
Q

Which of the following is NOT an absolute contraindication to the insertion of rescue cervical cerclage?

a. Maternal infection
b. Known GBS carriage
c. Vaginal bleeding
d. Ruptured membranes
e. Uterine contractions

A

B - Known GBS carriage

71
Q

What, according to National Institute for Health and Care Excellence guidance, would be the most appropriate intervention to offer a 28-year-old who presents at 25+6 weeks of gestation with threatened preterm labour?​

a. Cervical phosphorylated insulin-like growth factor binding globulin protein-1
b. Corticosteroids and tocolysis
c. Placental alpha macroglobulin-1
d. Translabial ultrasound to measure the cervical length
e. Vaginal fetal fibronectin

A

B - Corticosteroids and tocolysis

Based on cost-effectiveness, the recent National Institute of Health and Care Excellence (NICE) pathway on preterm birth and labour proposes that tests to help diagnosed labour in women with pregnancies below 29+6 weeks of gestation are not used after this gestation but rather these women should be administered corticosteroids and tocolysis.

TOG StratOG Resource

72
Q

When should antenatal corticosteroids be administered for neonatal benefit in women presenting with threatened or established preterm labour?

a. 20+0–34+6 weeks of gestation
b. 22+0–34+6 weeks of gestation
c. 24+0–34+6 weeks of gestation
d. 22+0–34+0 weeks of gestation
e. 24+0–36+0 weeks of gestation

A

C - 24+0–34+6 weeks of gestation

All women requiring or at a high risk of preterm delivery between 24+0 and 34+6 weeks of gestation should receive antenatal corticosteroids. These should also be considered for women at the threshold of viability (22+0–25+6 weeks of gestation) who are at risk of preterm birth.

TOG StratOG Resource