Malignant Melanoma Flashcards

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1
Q

What is it

A

An invasive malignant tumour of the epidermal melanocytes, which has the potential to metastasise

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2
Q

Risk factors

A
Excessive UV exposure 
Skin type 1 
History of multiple moles or atypical moles 
FH
Prev Hx of melanoma's
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3
Q

ABCDE Symptoms rule

A
Assymetrical shape 
Border irregular 
Colour irregular 
Diameter >6mm
Evolution of lesion (change in size and shape)

Symptoms - bleeding and itching

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4
Q

Where is it more common in men and women?

A

Trunk

Legs

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5
Q

Superficial spreading melanoma

  • Where and who is it common?
  • What is it related to?
A

Lower limbs
Young middle aged adults

Intermittent high intensity UV exposure

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6
Q

Nodular melanoma

  • Where and who is it common?
  • What is it related to?
A

Common on the trunk

In young and middle aged adults

Intermittent high intensity UV exposure

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7
Q

Lentigo Maligna Melanoma

  • Where and who is it common?
  • What is it related to?
A

Face

Elderly

Long term cumulative IV exposure

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8
Q

Acral Lentiginous Melanoma

  • Where and who is it common?
  • What is different about this one?
A

Palms, soles and nail beds

Elderly

No clear relation with UV exposure

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9
Q

Management - 3

What is Breslow’s thickness used to predict?

A

Surgical excision
Radiotherapy
Chemotherapy

Used to predict the recurrence of melanoma

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