Malignant bone tumours

Question 1

What is the commonest primary cancer within bone?

Answer 1

Multiple myeloma

Question 2

Multiple myeloma is a malignancy of what cells?

Answer 2

Plasma cells

Question 3

What tumour is associated with the chromosomal translocation - t11:22?

Answer 3

Ewing’s sarcoma

Question 4

Which of these tumours - Ewing’s sarcoma, osteosarcoma multiple myeloma and chondrosarcoma - are more associated with children and young adults, and which are more associated with middle aged and older adults?

Answer 4

Children and young adults = Ewing’s sarcoma and osteosarcoma
Middle aged + older = chondrosarcoma and multiple myeloma

Question 5

Which part of a bone is osteosarcoma most commonly associated with?

Answer 5

Metaphysis

Question 6

Name an xray feature of osteosarcoma

Answer 6

• Sunburst appearance
• Codman triangle

Question 7

Onion skin on xray is associated with what cancer?

Answer 7

Ewing’s sarcoma

Question 8

What is the commonest benign bone tumour?

Answer 8

Osteochondroma