Malignancies Flashcards
What is proliferative
Uncontrolled expansion of blood cells
What is dysplastic
Abnormal cell growth in tissue or organ
What is the dysplastic myeloid malignancies
Myeloid dysplastic syndrome
What are the proliferative myeloid diseases
Myeloproliferative neoplasm
What is the analysis of chronic myeloid leukaemia
Full blood count
Red cells low
White blood high
High platelet
What is chronic myeloid leukaemia
Too many white blood cells in bone marrow
What is the chromosome for CML
Philadelphia
What is immunophenotyping
Studies proteins expressed by cells
What is FISH
Fluorescence binds to nucelic acid sequence
What is treatment for cml
Tyrosine kinase inhibitors
What is acute myeloid leukaemia
Proliferation of blast cells
What’s the blood count for AML
Red cells low
White cells high
Platelets low
What are the blood tests
Full blood count and film
Bone marrow aspirate
Immunophenotyping
Karyotype
Fish
Genetics
Which are lymphoblasts
T cell
B cell
What are the myeloblasts
Granulocyted
Baso neutro eosinophils