Malignancies Flashcards

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1
Q

What is proliferative

A

Uncontrolled expansion of blood cells

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2
Q

What is dysplastic

A

Abnormal cell growth in tissue or organ

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3
Q

What is the dysplastic myeloid malignancies

A

Myeloid dysplastic syndrome

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4
Q

What are the proliferative myeloid diseases

A

Myeloproliferative neoplasm

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5
Q

What is the analysis of chronic myeloid leukaemia

A

Full blood count

Red cells low
White blood high
High platelet

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6
Q

What is chronic myeloid leukaemia

A

Too many white blood cells in bone marrow

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7
Q

What is the chromosome for CML

A

Philadelphia

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8
Q

What is immunophenotyping

A

Studies proteins expressed by cells

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9
Q

What is FISH

A

Fluorescence binds to nucelic acid sequence

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10
Q

What is treatment for cml

A

Tyrosine kinase inhibitors

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11
Q

What is acute myeloid leukaemia

A

Proliferation of blast cells

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12
Q

What’s the blood count for AML

A

Red cells low
White cells high
Platelets low

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13
Q

What are the blood tests

A

Full blood count and film
Bone marrow aspirate
Immunophenotyping
Karyotype
Fish
Genetics

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14
Q

Which are lymphoblasts

A

T cell
B cell

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15
Q

What are the myeloblasts

A

Granulocyted
Baso neutro eosinophils

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16
Q

What is reverse transcriptase

A

RNA to dna

17
Q

What is aml treatment

A

Chemo
Drugs from immunophenotyping