Male Genital System I

Question 1

Dx?

Answer 1

Epispadias

(Epi = dorsal; hypo = ventral)

Question 2

Dx?

Answer 2

Condyloma acuminatum

(HPV 6 or 11)

Question 3

Will this patient be able to reproduce?

Answer 3

Yes! Focal atrophy indicates mumps, which is generally unilateral and patchy, preserving fertility

Question 4

“It doesn’t hurt.” Dx?

Answer 4

Chancre of primary syphilis

Question 5

Risk factors?

Answer 5

HPV 16 and 18, smoking, poor hygiene, being uncircumcised

Question 6

Dx?

Answer 6

Phimosis

(Inability to retract foreskin)

Question 7

This patient presents with reproductive difficulty. Genotypic studies would reveal ___ and histology of his testicles would reveal ___.

Answer 7

Most likely 47,XXY

Hyalinized seminiferous tubules and pseudoadenomatous clusters of Leydig cells

Question 8

This infection started in the prostate then moved to the epididymis. Dx?

Answer 8

TB

(Pattern of spread + caseating granuloma)

Question 9

A newborn with 46,XY genotype presents with undescended testes. What other congenital anomaly should you check for?

Answer 9

Hypospadias

(Often associated with undescended testes)

Question 10

This guy is at an increased risk for _____ but decreased risk for _____.

Answer 10

Squamous cell carcinoma of penis

HIV transmission from a female

Question 11

Cause?

Answer 11

HPV 6 or 11

(Notice cauliflower-like growths)

Question 12

Pattern of spread of this organism?

Answer 12

Testis –> epididymis

(Spirochetes = syphilis)

Question 13

John is a 65 yo white male who presents with dysuria and frequency of urination that resolves with antibiotic therapy. Two months later, however, he presents with an enlarging testicle. What would you expect on histology?

Answer 13

INTRATUBULAR histiocytes + lymphocytes + plasma cells = Idiopathic granulomatous orchitis

(Usually follows a gram negative UTI)