male Canine Flashcards

1
Q

what is part of a male dogs BSE?

A
  • General Physical
    • joint disease
    • back pain
    • neurological disease
  • Penis/Prepuce
    • persistent frenulum
    • vesicular, prolifertive inflammatory lesions
    • trauma
    • swelling
    • abrasions
    • penile tumors
    • lacerations
  • Palpation of the scrutum and scrotum contents
    • Two testes by 3-10 days
    • palpable by 5-8 wks
    • >6 months = cryptorchid
  • Palpation of the prostate
  • Semen evaluation:
    • color - milk-white
      • yellow = urine contamination or purulent exudate
      • red/borwn = fresh/hemolyzed blood
    • Volume -
    • pH 6.5-7.0
    • Motility
    • Concentration
    • morphology
    • Cytology
    • Longevity
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2
Q

What are the qualities of a satisfactory breeder?

A
  • Normal libido and gait
  • 2 scrotal testes
  • No scrotal, penile, or prostatic abnormalities
  • Free of Brucell canis
  • ≥ 70% progressively motile sperm
  • ≥80% morphologically normal sperm
  • ≥300x106 total sperm
    • OR ≥106sperm/lb body weight
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3
Q

What is azoospermia?

A
  • Failure of the testes to prouce sperm
  • Failure of sperm to exit the testes due to epididymal blockage
  • Incomplete ejaculation
  • During ejaculation alkaline phosphatase secreted by the epididymis
    • >5,000 IU/L indicates fluid from epididymis was collected but no sperm
      • tru azoospermia
    • <5,000 IU/L suggest epididymal blockage or ejaculation failure
      • repeat semen collection
      • allow natural mating and swab vagina for evidence of sperm
      • cystocentesis to rule-out retrograde ejaclation
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4
Q

What does a normal culture and cytology of semen contain?

A
  • Resident flora:
    • Staph spp
    • Strep spp
    • E. coli
    • Proteus mirabilis Klebsiella pneumonia
    • Hemphilus pp
    • Corynebacterium spp
    • moraxella spp
  • Cytology:
    • ≤6 WBC/hpg
    • Can see clinical significant growth of pathogenic bacteria w/ normal cytology
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5
Q

What is a prostate evaluation?

A
  • Only accessory sex gland in dogs
  • Bilobed, symmetric, non-painful, uniform consistency
  • Brim of the pelvis at the neck of the bladder
    • Retroperitoneal
    • Abdominal in larger dogs or prostatomegaly
      • Prostatomegaly ⇢ cranial displacement of the bladder
  • Digital palpation
    • location changes slightly with size and age
    • Subclinical prostatic disease without palbacle changes
  • Transabdominal US
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6
Q

What is benign prostatic hyperplasia?

A
  • Generalized enlargement of the prostate gland
    • increase in epithelial cell size (hypertrophy)
    • increase in epithelial cell number (hyperplasia)
  • 50% of intact males have histologic evidence of BPH by 5yrs old
    • part of the normal aging process
    • not all exhibit clinical signs
    • balanced by apoptosis
  • Affects nearly every intact male dog
    • mean age at time of diagnosis = 8yr
  • Estrogen mediated:
    • increasing the number of androgen receptors within the prostate
  • Testosterone is converted to Dihydrotestosterone (DHT) by 5a-reductase
    • DHT - active metabolite regulating prostatic growth and secretion
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7
Q

What are the clinical signs of BPH?

A
  • Asymptomatic
  • Tenesmus
  • Urethral discharge
    • serous or hemorrhagic
  • Hematuria
  • Hemospermia
  • Constipation
  • Dysuria
  • Stranguria
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8
Q

How is BPH diagnosed

A
  • Hx
  • Physical exam:
    • mild to moderate, symmetric, non-painful prostatomegaly
      • smooth contour and freely moveable
  • CBC/Chem - unremarkable
  • US - symmetric prostatomegaly with variable echogenicity
  • Abdominal radiographs
    • prostatomegaly
      • diameter >70% of the distance form the pubic brim to the sacrum
      • Width > 50% pelvic inlet
  • Cytology of prostatic fluid
  • Definitive dx = biopsy
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9
Q

What is the treatmetn for BPH

A
  • Indicated for those with clinical signs of prostatic disease
  • Castration:
    • 7-10 days decrease in prostatic size on rectal palation or imaging
    • 50% reduction w/in 3 wks
    • 70% reduction w/in 9wks
  • If Reduction in size does not occur reconsider diagnosis
  • Temporary Medical Therapy
    • Finasteride: 0.1-0.5 mg/kg/day PO
      • Inhibits 5a-reductase
    • 33-50% reduction in size by 6wks of treatment
    • Prostate returns to pre-treatment size w/in 2months of disconinuation
    • Does not affect semen quality
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10
Q

What is prostatitis

A
  • Inflammatory disese of the prostate gland commonly due to bacterial infection often superimposed over BPH
  • Occurs in both intact and neutered males
  • Ascending infection > hematogenous
    • E. coli
    • Staph, Strep, Proteus mirabilis, Klebsiella, Enterobacter, Pseudomonas, Brucella canis
    • hematogenous or extension from orchitis or epididmytis
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11
Q

What are the clinical signs of prostatitis

A
  • Acute:
    • anorexia
    • depression
    • vomiting
    • fever
    • stilted gait
    • caudal abdominal pain
    • Decreased libido
    • Urethral discharge
    • Painful when ejaculating
  • Chronic:
    • subclinical
    • Recurrent UTI
    • Urethral discharge
    • Poor semen quality
  • Prostatic abscesses may develop
    • peritonitis
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12
Q

How is Prostatitis diagnosed

A
  • +/- prostatomegaly, pain, asymmetry
  • +/- neutrophilia with left shift
  • Urinalysis - pyuria, bacteriuria, hematuria
  • Radiographs - prostatomegaly
  • US - focal or diffuse hypoechoic changes
  • Culture of prostatic fluid
  • Cytology of prostatic fluid - inflammatory
  • Retrograde cystourethrography
    • contrast may fill cystic spaces
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13
Q

How is prostatitis treated?

A
  • Supportive care
  • antibiotics fo 3-6wks
    • penetration into blood-prostatic barrier
      • lipid soluble, low protein binding, weak bases
      • Trimethoprim-sulfa, chlorampheicol, enrofloxacin, ciprofloxacin, marbofloxacin
  • Repeat culture in 1 wk and 4wks after tehrapy
  • Treat underlying BPH
    • castration
    • finasteride
  • Prostatic abscess:
    • US guided aspiration
    • Surgical Drainage
    • Antibiotic
    • Castration
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14
Q

What is prostatic neoplasia

A
  • Uncontrolled, disorganized proliferation of prostatic tissue
  • 3.5-15% prostatic disease
  • Intact or neutered, and older
  • Malignant carcinoma most common
    • adenocarcinoma or extension of transitional cel carcinoma
  • metastasis
    • iliac LN
    • Lungs
    • Urinary bladder
    • periprostatic tissue
    • rectum
    • bone
    • kidney
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15
Q

Clinical signs of prostatic neoplasia

A
  • Varies with pattern of metastasis
  • weight loss
  • inappetence
  • stilted gait
  • tenesmus
  • lumbar pain
  • stranguria
  • Rear limb weakness
  • Dysuria/hematuria/pyuria
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16
Q

How is prostatic neoplasia diagnosed and treated

A
  • History and PE similar to BPH and chronic prostatits
  • Rectal palpation - asymmetrically enlarged, firm, painful +/- nodular areas
    • +/- enlarged sublumbar ln
  • US and radiographs
    • prostatomegaly
    • intraprostatic mineralization
    • asymmetry
    • variable echogenicity
  • Biopsy
  • Prognosis: grave
  • Treatment - euthanasia
    • chemotherapy