Malaria Flashcards
When should you avoid malaria?
Asplenic + pregnant
What are the symptoms of malaria?
- High temp >38
- Chills
- Headache
- Muscle aches
- Di + vom
What is used for bite prevention?
- Personal protection (Counsel: warn about importance of avoiding mosquito bites)
- Net impregnated w permethrin
- DEET 20-50% 2M (apply sunscreen first)
- Long sleeves + trousers after dusk
What drugs are used for chemoprophylaxis?
Chloroquine
- MHRA: chloroquine: psychiatric reactions
Chloroquine + proguanil
Doxycycline 12+
- Counsel: 100mg OD: take 1-2 before entering endemic area + continue for 4 weeks after leaving
Malarone
Mefloquine
- Counsel: report new or worsening mental health symptoms, be careful when driving
Which drugs do you avoid in epilepsy?
Avoid chloroquine + mefloquine
Which drugs do you avoid in renal impairment?
- Avoid proguanil
- Malarone eGFR <30
Which drugs do you take when pregnant?
- Chloroquine + proguanil (5mg folic acid daily)
- Doxycycline CI
How do you take malaria prophylaxis when taking warfarin?
- Start 2-3 weeks before travel
- Stable INR: monitor before, 7 days after start + completion
What is the treatment after being dianosed with malaria?
Standby treatment eg quinine
- Access to medical care 24+H away
- Written instructions: if fever >38 for 7+ days - urgent care
Any illness w/in 1 year/3 months of return
- Counsel: promptly see doctor if any illness + mention malaria exposure
Regimes: malarone
- Before travel: 1-2 days
- After travel: 1 week
- LT use: 1 year
- Avoid: severe RI
- How to take: OD
Regimes: doxycycline
- Before travel: 1-2 days
- After travel: 4 week
- LT use: 2 year
- Side effect: photosensitive, esophageal irritation
- Avoid: pregnancy + breast feeding, under 12
- How to take: OD
Regimes: mefloquine
- Before travel: 2-3 weeks
- After travel: 4 week
- LT use: 1 year
- Side effect: psychiatric reactions
- Avoid: epilepsy
- How to take: once weekly
Regimes: proguanil
- Before travel: 1 week
- After travel: 4 week
- Avoid: RI
- How to take: OD
Regimes: chloroquine
- Before travel: 1 week
- After travel: 4 week
- Side effect: psychiatric reactions
- Avoid: epilepsy, severe RI
- How to take: once weekly
Regimes: chloroquine + proguanil
- Before travel: 1 week
- After travel: 4 week
- Side effect: psychiatric reactions
- Avoid: epilepsy, RI