Malabsorption Flashcards
1
Q
define malabsorption
A
defective mucosal absorption
2
Q
what is malabsorption caused by?
A
- defective luminal digestion
- mucosal disease
- structural disorders
3
Q
name the 4 malabsorbptive states
A
- protein
- fat
- carbohydrate
- vitamins and minerals
4
Q
what are the 2 types of protein malabsorption ?
A
digestive and absorptive
5
Q
what is digestive protein malabsorption?
A
- partial or total gastrectomy
- exocrine pancreatic insufficiency
- trypsinogen deficiency
- congential
6
Q
what is absorptive protein malabsorption?
A
- celiac disease and tropical sprue
7
Q
what are the 3 types of fat digestion and absorption malabsorption?
A
- digestive (pancreas and liver)
- absorptive (jejunal mucosa)
- post absorptive (Lymphatics)
8
Q
when would you suspect malabsorption?
A
- in known disease states
- past medical history
- drugs, social, travel
9
Q
malabsorption symptoms?
A
- diarrhoea
10
Q
malabsorption signs?
A
- easy bruising
- acrodermatitis enteropathica
- dermatitis herpetiformis
- glossitis and angular stomatitis
- spooning of nails
11
Q
what are the baseline investigations?
A
- FBC
- coagulation
- albumin
- LFTs
- calcium/magnesium
- stool culture
12
Q
what are the anatomic investigations?
A
- endoscopy
- imaging
13
Q
what is the management?
A
- treat underlying cause
- replace deficiency
- support nutritionally
