Malabsorption Flashcards

1
Q

define malabsorption

A

defective mucosal absorption

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2
Q

what is malabsorption caused by?

A
  • defective luminal digestion
  • mucosal disease
  • structural disorders
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3
Q

name the 4 malabsorbptive states

A
  1. protein
  2. fat
  3. carbohydrate
  4. vitamins and minerals
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4
Q

what are the 2 types of protein malabsorption ?

A

digestive and absorptive

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5
Q

what is digestive protein malabsorption?

A
  • partial or total gastrectomy
  • exocrine pancreatic insufficiency
  • trypsinogen deficiency
  • congential
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6
Q

what is absorptive protein malabsorption?

A
  • celiac disease and tropical sprue
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7
Q

what are the 3 types of fat digestion and absorption malabsorption?

A
  1. digestive (pancreas and liver)
  2. absorptive (jejunal mucosa)
  3. post absorptive (Lymphatics)
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8
Q

when would you suspect malabsorption?

A
  • in known disease states
  • past medical history
  • drugs, social, travel
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9
Q

malabsorption symptoms?

A
  • diarrhoea
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10
Q

malabsorption signs?

A
  • easy bruising
  • acrodermatitis enteropathica
  • dermatitis herpetiformis
  • glossitis and angular stomatitis
  • spooning of nails
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11
Q

what are the baseline investigations?

A
  • FBC
  • coagulation
  • albumin
  • LFTs
  • calcium/magnesium
  • stool culture
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12
Q

what are the anatomic investigations?

A
  • endoscopy

- imaging

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13
Q

what is the management?

A
  • treat underlying cause
  • replace deficiency
  • support nutritionally
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