malabsorption Flashcards
problems from post-gastrectomysyndrome and what kind of anaemia does it produce
Rapid emptying of food from stomach into the duodenum: diarrhoea, abdominal pain, hypoglycaemia
Complications: Vitamin B12 and iron malabsorption, osteoporosis
-pernicious anaemia as lack of intrinsic factor for b12
treatment of post gastrectomy syndrome
Treatment: High protein, low carbohydrate diet. Replace B12/Fe/Ca
what function does the stomach have in digestion
- intrinsic factor binds to b12
- pepsin digests protein
what secretes pepsin
chief cells
what secretes gastric acid
parietal cells
what is absorbed in the duodenum
- bile salts/lipases break down triglycerides so absorb fatty acids
- proteases break down protein so amino acids absorbed
- amylase breaks down cho so disaccharides absorbed
where is iron absorbed
end of duodenum
what is absorbed in the jejunum
- calcium
- folate
- fat soluble vitamins
- ffa
- monoglycerides
- b12
- water
- sodium
what is absorbed in the ileum
-bile salt acids
-b12
-intrinsic factor
water and sodium
what does the colon absorb
- some bile acids
- water
- electrolytes
what is short bowel syndrome
dehydration and malabsorption when massive intestinal resection especially of the ileum
- malabsorb bile salts especially and b12 so get increased fat loss
- malabsorb carbs produces diarrhoea
- malabsorb trace elements eg zinc if jejunum affected
glut 1 found
brain
glut 2 found
liver kidney intestine and pancreas
glut 3 found
on the brain
low kM so constant uptake rate to blood glucose
glut 4 found and what is it responsive too
muscle and heart and adipose responds to insulin
