Major B+T Cell Fx Flashcards

1
Q

B and T cells are what type of immunity

A

Adaptive

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2
Q

B cells are what branch of adaptive immunity

A

Humoral

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3
Q

How does a B Cell work

A

Recognizes and presents the antigen, somatic hypermutation happens to ensure ID of antigen, production of Antibody/Ig after they become plasma cells

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4
Q

What retains the ability to ID infections?

A

B memory cells

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5
Q

T cells are what branch of immunity

A

Cell mediated

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6
Q

T cell mechanisms

A

Th1+2 help B cells make antibodies by being part of costimulation
Also help them release the cytokines to recruit phagocytes and activate other WBC

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7
Q

T helper cells have what MHC/CD

A

T helpers have CD4 and are MHC2

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8
Q

Cytotoxic T cells have what CD/MHC

A

CD8 and MHC1

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9
Q

What type of hypersensitivity are T cells involved in

A

Type 4 hypersensitivity, or DTH (Delayed Type Hypersensitivity)

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10
Q

T cells can affect transplants how

A

By causing acute and chronic organ rejection

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11
Q

How do Tcytotoxic cells work

A

They use the same pathway as NK cells (perforin>granzyme>DNA>BAX>BCL2 removal from mitochondria>cytochrome C and caspase destruction

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