HLA disease

Question 1

What is B27 associated with

Answer 1

PAIR- Psoriatic Arthritis, Ankylosing Spondylitis, IBD-assoc arthritis, Reactive arthritis
ie seronegative arthropthies

Question 2

B57 is associated with

Answer 2

Abacavir sensitivity

Question 3

DQ8/DQ2 is associated with

Answer 3

Celiac’s disease- I 8 2 much gluten from DQ

Question 4

DR3 is associated with

Answer 4

DMT1, SLE, Grave’s disease, Hashimotos Thyroiditis, Addison disease

DMT1 is associated with DR3 and 4
- so T1 + HLA3=HLA4

Question 5

DR4 is associated with

Answer 5

DMT1, Rheumatoid Arthritis, and Addison disease

Rheum-atoid + DR4=rooms have a door and 4 walls