Maintenance Inhalers: Long Acting Antimuscarinics

Question 1

How do LAMAs work?

Answer 1

They block the bronchoconstrictor effects of acetylcholine on M3 and M2 receptors.

Question 2

What is the brand name of aclidinium?

Answer 2

Turdorza Pressair

Question 3

What inhaler form is Turdorza Pressair available in?

Answer 3

DPI

Question 4

What age groups can Turdorza Pressair be used for?

Answer 4

Adults (COPD) only

Question 5

What is the brand name of glycopyrrolate?

Answer 5

Seebri Neohaler

Question 6

What inhaler forms is glycopyrrolate available in?

Answer 6

DPI and nebulizer solution

Question 7

What age groups can glycopyrrolate be used for?

Answer 7

Adults (COPD) only

Question 8

What is the brand name for revefenacin?

Answer 8

Yupelri

Question 9

What form is Yupelri available in?

Answer 9

Nebulizer solution

Question 10

What age groups can Yupelri be used for?

Answer 10

Adults (COPD) only

Question 11

What is the brand name for tiotropium?

Answer 11

Spiriva

Question 12

What inhaler forms is tiotropium available in?

Answer 12

HandiHaler and Respimat

Question 13

What age groups an tiotropium be used for?

Answer 13

Children 5-11 years old and adults

Question 14

What is the brand name for umeclidinium?

Answer 14

Incruse Ellipta

Question 15

What inhaler form is umeclidinium avaiable in?

Answer 15

DPI

Question 16

What age groups can Incruse Ellipta be used for?

Answer 16

Adults (COPD) only

Question 17

What adverse effects are associated with LAMAs?

Answer 17

• Dry mouth
• Dizziness
• Blurred vision
• Upper respiratory infections
• Paradoxical bronchospasms

Question 18

Give one clinical pearl for LAMAs.

Answer 18

Tiotropium has been approved for use in asthma as an add-on option for children 12 years and older.