Macrolides Flashcards
Semisynthetic derivatives of erythromycin
Azithromycin
Clarithromycin
2 sugars of erythromycin
Desosamine
Cladinose
Drugs under macrolides
Erythromycin
Clarithromycin
Azithromycin
Ketolides
Erythromycin is fairly stable at what temperature
4 degrees celcius (loose activity at 20 degrees and at acid pH)
Drug of choice for corynebacterial infections
Erythromycin
T/F erythromycin is not removed by dialysis
True
Recommended prophylaxis against endocarditis during dental procedures in individuals with valvular heart disease
Erythromycin (but replaced by clindamycin)
Major metabolite of clarythromycin
14 hydroxyclarithromycin
A macrolide that may be associated with a small increased of cardiac death
Azithromycin
Give the drug sub class of ketolide
Teithromycin
A chlorine-substituted derivative of lincomycin, an antibiotic that is elaborated by Streptomyces lincolnensis
Clindamycin