MAAM CHA PART 1 HAHAHA Flashcards
A defensive reaction intended to neutralize, control or eliminate offending agent and to prepare the site for repair
Inflammation
What releases blood-clotting proteins at wound site?
Platelets from blood
What secrete factors that mediate vasodilation and vascular constriction, delivery of blood, plasma and cells to injured area increases
Mast cells
What does neutrophils secrete?
Neutrophils secrete factors that kill and degrade pathogens
What are the 5 cardinal signs of inflammation?
- Redness
- Heat
- Swelling
- Pain
- Loss of function
What do you call the process where neutrophils and macrophages remove pathogens?
phagocytosis
What hormone does macrophages secrete?
cytokines
What is the function of cytokines?
Attract immune system cells to the site and activate cells involved in tissue repair
3 chemical substances
- Histamine
- Kinins
- Prostaglandins
What does histamine help with?
Vasodilation and increase capillary permeability
What does kinins help with?
Attract neutrophils
What does prostaglandin help with?
Increase capillary permeability
What are the systemic responses to inflammation?
- Fever
- Pyrogens
- Leukocytosis
- Malaise, loss of appetite, aching, weakness
Occur to provide the body with greater ability to fight infection
Leukocytosis
Types of Inflammation
- Acute
- Chronic
- Subacute
Describe acute inflammation
- Local vascular and exudative changes
- Protective
- 2 weeks healing
Describe chronic inflammation
- Persists, not beneficial, not protective
- Month, years
- Debilitating and long lasting effect
- repair
Describe subacute inflammation
- Between acute and chronic