M5 Pathology Flashcards
5 Signs of systemic involvement
- Fevered carcass
- Petechial haemorrhages
- Acute or active abscesses
- Other acute/active lesions
- Enlarged spleen
How disease gets into an animal
- Inhalation
- Ingestion
- Trauma
- Congenital
- Copulation
Causes of disease (4)
- Physical - migrating parasites
- Physiological - emaciation
- Chemical - ISL, adenocarcinoma
- Infectious - bacteria, virus, parasites
How does disease spread
Tissue to tissue
Tissue spaces
Blood
Lymph
What do Parasites do?
- Cause extensive tissue damage
- Rob the host of food
- Mechanical obstruction of passages by compression of organs
- Cause traumatic damage
- Cause secondary infections by bacteria
6 Bacteria examples
- Tetanus
- TB
- Lepto
- Listeria
- CLA
- Gangrene
6 Viral examples
- Foot and mouth
- Influenza
- Scrapie
- Hepatitis
- ORF
- AIDS
6 Parasite examples
- Lice
- Ticks
- Fleas
- Worms
- Hydatids
- Liver fluke
- Trichinosis
How does bacteria cause disease?
They produce and secrete toxins and destroy tissues
- evade WBC
- turn off (trick)
- interfere with temperature
- attack healthy cells
Disease process (9)
- Cell damage
- Chemotaxis
- Hyperaemia
- Inflammatory exudate (forms fibrin)
- Fibrin forms around infection
- Abscess
- Fibrin forms over the infection
- Repair
- Resolved
Describe how pathogens invade the body via inhalation
A pathogen can be breathed in, in the form of dust or fumes or carried in with oxygen. They attach to the mucus of the mouth and carried to the pluck (or GIT)
Describe how pathogens invade the body via Ingestion
A pathogen can be taken to the GIT through the fodder
Describe how pathogens invade the body via Trauma
Any physical injury or wound (tripping/shearing/docking, arthritis) may cause formation of an abscess as the result of infection, migrating parasites
Describe how pathogens invade the body via parasites
Destroy tissues and organs, rob the host of food, and can cause secondary infection by bacteria and transmitting other diseases
Describe how bacteria in a liver abscess can spread to the spleen
Contiguous spread from tissue to tissue (close proximity)