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AUBF > M3:U3 Blood Porphobilinogen Bilirubin Urobilinogen > Flashcards

M3:U3 Blood Porphobilinogen Bilirubin Urobilinogen Flashcards

1
Q

Increase in rbc

A

Hematuria

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2
Q

Increase in hemoglobin due to lysis of rbc or prolonged standing

A

Hemoglobinuria

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3
Q

heme containing compounds that are also positive in chemical test

A

Hemoglobin
myoglobin
intact rbc
cytochrome

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4
Q

Porphyrin precursor intermediate compound in heme synthesis

A

Porphobilinogen

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5
Q

Orange yellow pigment formed by heme containing proteins

A

Bilirubin

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6
Q

Colorless compound formed from deconjugation of bilirubin

A

Urobilinogen

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7
Q

20% of urobilinogen are reabsorbed and reduced to

A

stercobilinogen

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8
Q

2% to 5% of urobilinogen

A

Excreted in urine

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9
Q

Hemoglobin is normally bound to ___ in the bloodstream

A

Haptoglobin

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10
Q

When all of haptoglobin has already been bound this can easily pass through the gfb

A

Free hemoglobin

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11
Q

Pathway of free hemoglobin in the kidney

A

reabsorbed in PCT
catabolized to ferritin by RTC
denatured to hemosiderin
Within 2 to 3 days after hemolytic episode

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12
Q

Caused by presence of intravascular hemolysis where rbcs are lysed prior to reaching gfb

A

True hemoglobinuria

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13
Q

Results from rbc lysis in urinary tract or urine due to alkaline or hypotonic urine more common

A

Pseudo hemoglobinuria

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14
Q

Differentiate true hemoglobinuria versus pseudo hemoglobinuria

A

Presence of hemosiderin granules (tested through prussian blue test)

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15
Q

Release due to muscle damage

A

Myoglobinuria

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16
Q

Hemoglobinuria or myoglobinuria:
More toxic to renal tubules

A

Myoglobinuria

17
Q

Hemoglobinuria or myoglobinuria:
Less toxic to renal tubules

A

Hemoglobinuria

18
Q

Hemoglobinuria or myoglobinuria:
Red or pink serum color

A

Hemoglobinuria

19
Q

Hemoglobinuria or myoglobinuria:
Normal pale yellow serum

A

Myoglobinuria

20
Q

Hemoglobinuria or myoglobinuria:
Decrease to absent haptoglobin

A

Hemoglobinuria

21
Q

Hemoglobinuria or myoglobinuria:
Normal haptoglobin

A

Myoglobinuria

22
Q

Hemoglobinuria or myoglobinuria:
Increase creatinine kinase, < 10x upper limit

A

hemoglobinuria

23
Q

Hemoglobinuria or myoglobinuria:
Increased creatinine kinase, > 10x upper limit

A

Myoglobinuria

24
Q

Hemoglobinuria or myoglobinuria:
Ammonium sulfate Precipitation test precipitated

A

Hemoglobinuria

25
Q

Hemoglobinuria or myoglobinuria:
Ammonium sulfate precipitation test soluble

A

Myoglobinuria

26
Q

Also known as ammonium sulfate precipitation test

A

Blondheim test

AUBF (12 decks)

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