M1 blood derivatives Flashcards
cold ethanol fractionation process
Cohn Fractionation
He Paved the way for the discovery of blood component therapy
EDWIN COHN (1940)
It allows the plasma to be broken down into albumin, gamma globulin and fibrinogen among other constituents.
Cohn Fractionation
This prevents circulatory overload
Cohn fractionation
Revolutionized the treatment of Hemophilia A
POOL AND SHANNON (1961)
They recognized that the precipitate formed when plasma was thawed in a cold cryo precipitate containing Factor VIII.
POOL AND SHANNON (1961)
What did Pool and Shannon add to the cold cryo precipitate to treat Hemophilia A
Factor VIII
1st AHF Concentrate
1962
Treats coagulation disorders
1st AHF Concentrate
This prevents Rh diseases in newborns of Rh negative women.
Rh Immune Globulin
The year Rh Immune Globulin was introduced commercially.
1967
The yearDry-heated, lyophilized Factor VIII and IX concentrates became available.
1985
The year Genetically engineered (recombinant) Factor VIII became available.
1993